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Profile of salivary gland flow dysfunctions in patients with differentiated thyroid carcinoma submitted to radioiodine therapy
Remote (Português (Brasil))

Keywords

Thyroid gland tumors
Iodine radioisotopes
Salivary glands
Saliva
Xerostomia
Hyposalivation

How to Cite

1.
Vieira ACF, Rodrigues ASL, Cruz MCFN da, Lopes FF. Profile of salivary gland flow dysfunctions in patients with differentiated thyroid carcinoma submitted to radioiodine therapy. Braz. J. Oral Sci. [Internet]. 2015 Oct. 16 [cited 2024 Mar. 1];12(3):169-72. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641016

Abstract

Aim: To evaluate the effects of radioiodine therapy on salivary flow in patients with differentiated thyroid cancer. Methods: A sample comprising 88 patients submitted to ablation with iodine 131 was included in the study. The patients were submitted to sialometry and evaluation of the presence of xerostomia before, 10 days and 3 months after radioiodine therapy. Results: Xerostomia was observed in 36.4% of the patients before radioiodine therapy, 59.15% at 10 days after therapy, and 25% at 3 months after therapy. Significant differences were observed in non-stimulated salivary flow rates between the second and third evaluations (p<0.020) and in stimulated salivary flow between the first and second evaluations (p<0.010). Conclusions: The results suggest that changes in salivary flow resulting from radioiodine therapy are more pronounced during the first weeks after treatment and seem to regress after 3 months.
Remote (Português (Brasil))
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2015 Anna Clara Fontes Vieira, Aline Sampaio Lima Rodrigues, Maria Carmen Fontoura Nogueira da Cruz, Fernanda Ferreira Lopes

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