Profile of salivary gland flow dysfunctions in patients with differentiated thyroid carcinoma submitted to radioiodine therapy

Authors

  • Anna Clara Fontes Vieira Federal University of Maranhão
  • Aline Sampaio Lima Rodrigues Federal University of Maranhão
  • Maria Carmen Fontoura Nogueira da Cruz Federal University of Maranhão
  • Fernanda Ferreira Lopes Federal University of Maranhão

DOI:

https://doi.org/10.20396/bjos.v12i3.8641016

Keywords:

Thyroid gland tumors, Iodine radioisotopes, Salivary glands, Saliva, Xerostomia, Hyposalivation

Abstract

Aim: To evaluate the effects of radioiodine therapy on salivary flow in patients with differentiated thyroid cancer. Methods: A sample comprising 88 patients submitted to ablation with iodine 131 was included in the study. The patients were submitted to sialometry and evaluation of the presence of xerostomia before, 10 days and 3 months after radioiodine therapy. Results: Xerostomia was observed in 36.4% of the patients before radioiodine therapy, 59.15% at 10 days after therapy, and 25% at 3 months after therapy. Significant differences were observed in non-stimulated salivary flow rates between the second and third evaluations (p<0.020) and in stimulated salivary flow between the first and second evaluations (p<0.010). Conclusions: The results suggest that changes in salivary flow resulting from radioiodine therapy are more pronounced during the first weeks after treatment and seem to regress after 3 months.

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Author Biographies

Anna Clara Fontes Vieira, Federal University of Maranhão

Department of Dentistry, Dental School, Federal University of Maranhão, São Luís, MA.

Aline Sampaio Lima Rodrigues, Federal University of Maranhão

Department of Dentistry, Dental School, Federal University of Maranhão, São Luís, MA.

Maria Carmen Fontoura Nogueira da Cruz, Federal University of Maranhão

Department of Dentistry, Dental School, Federal; Oral Pathology Department, Dental School, Federal University of Maranhão, São Luís, MA.

Fernanda Ferreira Lopes, Federal University of Maranhão

Department of Dentistry, Dental School, Federal; Oral Pathology Department, Dental School, Federal University of Maranhão, São Luís, MA.

Published

2015-10-16

How to Cite

1.
Vieira ACF, Rodrigues ASL, Cruz MCFN da, Lopes FF. Profile of salivary gland flow dysfunctions in patients with differentiated thyroid carcinoma submitted to radioiodine therapy. Braz. J. Oral Sci. [Internet]. 2015 Oct. 16 [cited 2022 Sep. 29];12(3):169-72. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641016

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