Oral antibacterial effect of chlorhexidine treatments and professional prophylaxis in children

Authors

  • Thiago Cruvinel Silva USP
  • Thaís Marchini Oliveira Valarelli USP
  • Vivien Thiemy Sakai Alfenas Federal University
  • Vanessa Tessarolli USP
  • Maria Aparecida de Andrade Moreira Machado USP

DOI:

https://doi.org/10.20396/bjos.v12i2.8641100

Keywords:

Aggressive periodontitis, Professional prophylaxis, Chlorhexidine, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Streptococcus mutans

Abstract

Aim: The primary aim of this longitudinal study was to evaluate additional effects of 4-week chlorhexidine digluconate (CHX) gel treatments to control Aggregatibacter actinomycetemcomitans counts in children after professional dental prophylaxis. Porphyromonas gingivalis and Streptococcus mutans counts were also determined to evaluate the secondary effects of anti-plaque treatments on microbial shifts. Methods: Twenty-six children with A. actinomycetemcomitans counts >4 log10/ mL of saliva and/or Quigley-Hein plaque index >3.0 were enrolled in this study. Patients were randomly assigned to groups GI (placebo gel), GII (0.5% CHX gel), GIII (1% CHX gel), and GIV (2% CHX gel). Four sessions of treatment were performed during 4 weeks after a session of professional dental prophylaxis. Real-Time polymerase chain reaction (PCR) was used to determine viable microorganism counts in non-stimulated whole saliva samples collected at baseline, one week, one month and three months after interruption of treatments. Results: A reduction of all bacterial counts was detected after the 3-month follow-up in all groups. Lower counts of P. gingivalis were achieved from 1 week on after treatments. The 2% CHX concentration seemed to contribute to lower A. actinomycetemcomitans levels and increase S. mutans levels. Conclusions: Professional dental prophylaxis was effective to control salivary levels of A. actinomycetemcomitans, P. gingivalis and S. mutans. Additional antimicrobial effects, however, were not observed by the combination of professional dental prophylaxis and 4-week chlorhexidine gel treatments.

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Author Biographies

Thiago Cruvinel Silva, USP

Department of Pediatric Dentistry, Orthodontics, and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, SP.

Thaís Marchini Oliveira Valarelli, USP

Department of Pediatric Dentistry, Orthodontics, and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, SP.

Vivien Thiemy Sakai, Alfenas Federal University

Department of Clinic and Surgery, Alfenas, School of Dentistry, Alfenas Federal University, MG.

Vanessa Tessarolli, USP

Department of Pediatric Dentistry, Orthodontics, and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, SP.

Maria Aparecida de Andrade Moreira Machado, USP

Department of Pediatric Dentistry, Orthodontics, and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, SP.

Published

2015-10-16

How to Cite

1.
Silva TC, Valarelli TMO, Sakai VT, Tessarolli V, Machado MA de AM. Oral antibacterial effect of chlorhexidine treatments and professional prophylaxis in children. Braz. J. Oral Sci. [Internet]. 2015 Oct. 16 [cited 2022 Dec. 8];12(2):132-7. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641100

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