AbstractAim: To clarify the influence of 5.25% sodium hypochlorite disinfection of gutta-percha cones on leakage and to compare the outcomes of two sealability assessment methodologies (fluid filtration and dye penetration methods). Methods: Thirty teeth were prepared and filled using the guttapercha lateral condensation technique. Group I was filled with gutta-percha cones disinfected with sodium hypochlorite 5.25%, while Group II was filled with cones that were not disinfected. Apical leakage was measured using: (a) fluid filtration technique and (b) linear measurement of dye penetration after clearance. Results: The Student’s t-test showed no significant difference between the groups for both techniques (p<0.05). Conclusions: Both methodologies employed, even with the inherent limitations, were capable of identifying sealing failures. The disinfection of gutta-percha cones with 5.25% sodium hypochlorite did not alter apical leakage.
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