Risk factors for oral candidiasis in Brazilian HIV-infected adult patients

Authors

  • Mariela Dutra Gontijo Moura Federal University of Minas Gerais
  • Soraya de Mattos Camargo Grossman Federal University of Minas Gerais, Belo Horizonte
  • Linaena Méricy da Silva Fonseca Faculdades Pitágoras
  • Maria Letícia Ramos Jorge Federal University of Vales Jequitinhonha and Mucuri
  • Ricardo Alves Mesquita Federal University of Minas Gerais

DOI:

https://doi.org/10.20396/bjos.v9i4.8641742

Keywords:

AIDS, Candidiasis, HAART, HIV infection, Prevalence ratio, Risk factors

Abstract

Aim: The goals of this study were: 1) to estimate the prevalence of oral candidiasis (OC) in a sample of Brazilian HIV-infected adult patients, and 2) to investigate the risk factors for HIVassociated OC in this sample. Methods: This case-control study included 112 HIV-infected patients treated between 2002 and 2004 at a clinic for sexually transmitted diseases. Data were collected from medical records and clinical examinations. Diagnosis of OC was performed in accordance with the International Classification System and cytological features. Seventeen clinical and laboratorial variables were registered. Univariate analyses were performed on all variables. Multiple logistic regression techniques were used to develop a model and identify the set of variables that may predict risk factors in HIV-infected adult patients with OC. Results: Prevalence of OC was 31.3%. OC was associated with oral hairy leukoplakia (OHL) [p<0.001; odds ratio (OR) = 10.2 (95%CI: 4.0-26.0)], previous use of fluconazole [p<0.001; OR=27.4 (95%CI: 8.1-92.0)] and viral load [p=0.042; OR=2.3 (95%CI: 1.0-5.3)]. Conclusions: These results are important for the development of strategies to eliminate these risk factors and significantly reduce OC in HIV-infected patients.

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Author Biographies

Mariela Dutra Gontijo Moura, Federal University of Minas Gerais

MSc, Graduate students, Department of Oral Pathology, Dental School, Federal University of Minas Gerais, Belo Horizonte, MG

Soraya de Mattos Camargo Grossman, Federal University of Minas Gerais, Belo Horizonte

MSc, Graduate students, Department of Oral Pathology, Dental School, Federal University of Minas Gerais, Belo Horizonte, MG

Linaena Méricy da Silva Fonseca, Faculdades Pitágoras

PhD, Assistant Professor, School of Health, Faculdades Pitágoras, Belo Horizonte, MG

Maria Letícia Ramos Jorge, Federal University of Vales Jequitinhonha and Mucuri

PhD, Professor. Department of Dentistry, Federal University of Vales Jequitinhonha and Mucuri, Diamantina, MG

Ricardo Alves Mesquita, Federal University of Minas Gerais

PhD, Associate Professor, Department of Oral Pathology, Dental School, Federal University of Minas Gerais, Belo Horizonte, MG

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Published

2015-11-16

How to Cite

1.
Moura MDG, Grossman S de MC, Fonseca LM da S, Jorge MLR, Mesquita RA. Risk factors for oral candidiasis in Brazilian HIV-infected adult patients. Braz. J. Oral Sci. [Internet]. 2015 Nov. 16 [cited 2022 Oct. 7];9(4):470-4. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641742

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