Addison’s disease associated to paracocidioidomycosis


  • Claudio Maranhão Pereira School of Dentistry of Piracicaba, UNICAMP
  • Silmara Regina Silva Dentistry Section, Municipal Healthy Service
  • Priscila Spaziane Camargo Dentistry Section, Municipal Healthy Service
  • Andrea Mantesso Oral Pathology, São Leopoldo Mandic Dental Research Institute
  • Rodrigo Calado Nunes Souza Dentistry Section, Municipal Healthy Service



Addison’s disease. Paracoccidioidomycosis. Adrenal glands


Paracoccidioidomycosis is a deep mycosis caused by the Paracoccidioides brasiliensis and it has been considered the most frequent systemic mycosis in Latin America. Mulberry-like ulcers on the oral mucous membranes are one of the earliest manifestations of the disease. Infection may remain subclinical, localized or disseminate occasionally. Adrenal involvement by granulomatous diseases is the main cause of this gland insufficiency in Brazil. The aim of this study is to report one case of oral paracoccidoidomycosis that provided the diagnosis of the systemic mycosis disease with secondary Addison’s disease. In spite of not being rare the involvement of the adrenal glands for the P. brasiliensis, it was not possible to find in the literature another case with oral clinical and progression features similar to this.


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Author Biographies

Claudio Maranhão Pereira, School of Dentistry of Piracicaba, UNICAMP

graduate at odontologia from Universidade Federal de Goiás (1996), master's at Odontology from Universidade Estadual de Campinas (2002) and ph.d. at Odontology from Universidade Estadual de Campinas (2004). Has experience in Odontology, acting on the following subjects: gvhd, imunossupressão, cavidade bucal, transplante de medula óssea and hemorragia.

Silmara Regina Silva, Dentistry Section, Municipal Healthy Service

Possui graduação em Odontologia pela Faculdade de Odontologia de Piracicaba - UNICAMP (1995). Especialização em Estomatologia pelo Hospital Heliópolis (2001).(Texto informado pelo autor)

Priscila Spaziane Camargo, Dentistry Section, Municipal Healthy Service

Possui graduação em Odontologia pela Universidade Estadual Paulista Júlio de Mesquita Filho(1991) e residencia-medicapela Universidade Camilo Castelo Branco(2002). Atuando principalmente nos seguintes temas:Cirurgia Buco Maxilo Facial, Buco, Trauma Facial.

Andrea Mantesso, Oral Pathology, São Leopoldo Mandic Dental Research Institute

Bachelor's in dentistry from Universidade de São Paulo (1994) and doctorate at Odontology from Universidade de São Paulo (2000). Has experience in Odontology, focusing on Oral Pathology, acting on the following subjects: dental stem cells, histopathological diagnostics and oral cancer.

Rodrigo Calado Nunes Souza, Dentistry Section, Municipal Healthy Service

Possui graduação em Odontologia pela Universidade Estadual de Campinas(1997), especialização em Estomatologia pela Hospital Heliópolis - Unidade de Gestão Assistencial 1(2000), mestrado em Odontologia (Cirurgia e Traumatologia Buco-Maxilo Facial pela Universidade de São Paulo(2003), residencia-medicapela Hospital Municipal de Campinas Dr. Mário Gatti(2006) e aperfeicoamento em Pacientes Especiais pelo Associação de Assistência à Criança Deficiente de São Paulo(1999). 


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How to Cite

Pereira CM, Silva SR, Camargo PS, Mantesso A, Souza RCN. Addison’s disease associated to paracocidioidomycosis. Braz. J. Oral Sci. [Internet]. 2015Nov.16 [cited 2021Oct.27];3(9):475-8. Available from:



Case Report