Banner Portal
Oral hairy leukoplakia as a sign of HIV infection
Remote

Keywords

Oral hairy leukoplakia. Epstein-Barr virus. Cytopathology

How to Cite

1.
Silva Junior A, Nikitakis NG, Meeks V, Gracia CCB, Saraiva FMGC, Ferreira SMS, et al. Oral hairy leukoplakia as a sign of HIV infection. Braz. J. Oral Sci. [Internet]. 2015 Nov. 17 [cited 2024 Apr. 20];3(11):628-32. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641782

Abstract

Described for the first time in 1984, oral hairy leukoplakia (OHL) is strongly associated with human immunodeficiency virus (HIV) disease, although some cases have been reported in HIV negative individuals. After the introduction of highly active antiretroviral therapy, the prevalence of OHL in HIV patients declined significantly. OHL has been convincingly shown to be related to Epstein-Barr virus. Cytopathologic examination is considered the best method for OHL diagnosis. This report describes a case of OHL in an HIV patient, whose HIV status was unknown at the time of OHL diagnosis.
https://doi.org/10.20396/bjos.v3i11.8641782
Remote

References

Triantos D, Porter SR, Scully C, Teo CG. Oral hairy leukoplakia: clinicopathologic features, pathogenesis, diagnosis, and clinical significance. Clin Infect Dis 1997; 25: 1392-6.

Dias EP, Rocha ML, Silva A Jr, Spyrides KS, Ferreira SM, Polignano GA et al. Oral hairy leukoplakia. histopathologic and cytopathologic features of a subclinical phase. Am J Clin Pathol. 2000; 114: 395-401.

Dios PD, Ocampo A, Miralles C, Limeres J, Tomas I. Changing prevalence of human immunodeficiency virus-associated oral lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000; 90: 403-4.

Mabruk MJEMF, Flint SR, Coleman DC, Shiels O, Toner M, Atkins GJ. A rapid microwave in situ hybridization method for the definitive diagnosis of oral hairy leukoplakia: comparison with immunohistochemistry. J Oral Pathol Med 1996; 25: 170-6.

Southam JC, Felix DH, Wray D, Cubie HA. Hairy leukoplakia – histological study. Histopathology 1991; 19: 63-7.

Greenspan D, Greenspan JS, Conant M, Petersen V, Silverman S Jr, de Souza Y. Oral “hairy” leukoplakia in male homosexuals: evidence of association with both papillomavirus and a herpes – group virus. Lancet 1984; 2: 831-4.

Migliorati CA, Jones AC, Baughman PA. Use of exfoliative cytology in the diagnosis of oral hairy leukoplakia. Oral Surg Oral Med Oral Pathol 1993; 76: 704-10.

Greenspan JS, Barr EC, Sciubba JJ, Winkler JR. Oral manifestations of HIV infection. Definition, diagnostic criteria, and principles of therapy. The U.S.A. Oral AIDS Collaborative Group. Oral Surg Oral Med Oral Pathol 1992; 73: 142-4.

Neville BW, Damm DD, Allen CM, Bouquot JE. Viral Infections. In: Neville BW, Damm DD, Allen CM, Bouquot JE, editors. Oral & Maxillofacial Pathology. Philadelphia, PA: WB Saunders Co; 2002. p.213-52.

Schulten EA, Snijders PJ, ten Kate RW, Mullink H, Walboomers JM, Meijer CJ et al. Oral hairy leukoplakia in HIV infection: a diagnostic pitfall. Oral Surg Oral Med Oral Pathol 1991; 71: 32-7.

Epstein JB, Fatahzadeh M, Matisic J, Anderson G. Exfoliative cytology and electron microscopy in the diagnosis of hairy leukoplakia. Oral Surg Oral Med Oral Pathol 1995; 79: 564-9.

Kratochvil FJ, Riordan P, Auclair PL, Huber MA, Kragel PJ. Diagnosis of hairy leukoplakia by ultra structural examination of exfoliative cytologic specimens. Oral Surg Oral Med Oral Pathol 1990; 70: 613-8.

Resnick L, Herbst JS, Raab-Traub N. Oral hairy leukoplakia.

J Am Acad Dermatol 1990; 22: 1278-82.

Fraga Fernandez J, Benito C, Lizaldez EB, Montanes MA. Oral hairy leukoplakia: a histopathologic study of 32 cases. Am J Dermatopathol 1990; 12: 571-8.

Fraga Fernandez J, Vicandi-Plaza B. Diagnosis of hairy leukoplakia by exfoliative cytologic methods. Am J Clin Pathol 1992; 97: 262-6.

Narami N, Epstein JB. Classifications of oral lesions in HIV infection. J Clin Periodontol 2001; 28: 137-45.

Snijders PJ, Schulten EA, Mullink H, ten Kate RW, Jiwa M, van der Waal, et al. Detection of Human Papillomavirus and Epstein-Barr virus DNA sequences in oral mucosa of HIV – infected patients by the polymerase chain reaction. Am J Pathol 1990; 137: 659-66.

Khongkunthian P, Grote M, Isaratanan W, Piyaworawong S, Reichart PA. Oral manifestations in HIV-positive adults from Northern Thailand. J Oral Pathol Med. 2001; 30: 220-3.

Marcenes W, Pankhurst CL, Lewis DA. Oral health behaviour and the prevalence of oral manifestations of HIV infection in a group of HIV positive adults. Int Dent J 1998; 48: 557-62.

Muzyca BC, Kamwendo L, Mbweza E, Lopez NB, Glick M, Matheson PB et al. Prevalence of HIV-1 and oral lesions in pregnant women in rural Malawi. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 92: 56-61.

Patton LL, McKaig R, Strauss R, Rogers D, Eron JJ Jr. Changing prevalence of oral manifestations of human immunodeficiency virus in the era of protease inhibitor therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000; 89: 299-304.

Tappuni AR, Flemingo GJP. The effect of antiretroviral therapy on the prevalence of oral manifestations in HIVinfected patients: A UK study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 92: 623-8.

Fonseca R, Cardoso AS, Pomarico I. Frequency of oral manifestations in children infected with human immunodeficiency virus. Quintessence Int. 2000; 31: 419- 22.

Portela MB, Castro GF, Costa EM, Silva Junior A, Dias EP, de Souza IP. Case report on a rare lesion in an HIV-infected child: hairy leukoplakia. J Clin Pediatr Dent. 2002; 26: 405- 8.

Lozada-Nur F, Robinson J, Regezi JA. Oral hairy leukoplakia in nonimmunosuppressed patients:Report of four cases. Oral Surg Oral Med Oral Pathol 1994; 75: 599-602.

Epstein JB, Sherlock CH, Wolber RA. Hairy leukoplakia after bone marrow transplantation. Oral Surg Oral Med Oral Pathol 1993; 75: 690-5.

Fluckiger R, Laifer G, Itin P, Meyer B, Lang C. Oral hairy leukoplakia in a patient with ulcerative colitis. Gastroenterology 1994; 106: 506-8.

Schiodt M, Nogaard T, Greenspan JS. Oral hairy leukoplakia in an HIV-negative woman with Bechet’s syndrome. Oral Surg Oral Med Oral Pathol 1995; 79: 53-6.

Jahn S, Busch HW, Altmeyer P. Oral hairy leukoplakia in HIV -positive patients. J Am Acad Dermatol 1998; 38: 284-6.

Reichart PA. Clinical management of selected oral fungal and viral infections during hiv-disease. Int Dent J 1999; 49: 251-9.

The Brazilian Journal of Oral Sciences uses the Creative Commons license (CC), thus preserving the integrity of the articles in an open access environment.

Downloads

Download data is not yet available.