Dental cementum reviewed: development, structure, composition, regeneration and potential functions

  • Patricia Furtado Gonçalves School of Dentistry at Piracicaba
  • Enilson Antonio Sallum School of Dentistry at Piracicaba
  • Antonio Wilson Sallum School of Dentistry at Piracicaba
  • Márcio Zaffalon Casati School of Dentistry at Piracicaba
  • Sérgio Toledo School of Dentistry at Piracicaba
  • Francisco Humberto Nociti Junior School of Dentistry at Piracicaba
Keywords: Dental cementum. Review

Abstract

This article reviews developmental and structural characteristics of cementum, a unique avascular mineralized tissue covering the root surface that forms the interface between root dentin and periodontal ligament. Besides describing the types of cementum and cementogenesis, attention is given to recent advances in scientific understanding of the molecular and cellular aspects of the formation and regeneration of cementum. The understanding of the mechanisms involved in the dynamic of this tissue should allow for the development of new treatment strategies concerning the approach of the root surface affected by periodontal disease and periodontal regeneration techniques.

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Author Biographies

Patricia Furtado Gonçalves, School of Dentistry at Piracicaba
has graduation at Odontologia by Universidade Estadual de Campinas (1998) , master's at Clínica Odontológica by Universidade Estadual de Campinas (2002) , Ph.D. at Clínica Odontológica by Universidade Estadual de Campinas (2006) , Postdoctorate by University of Florida (2012) and aperfeicoamento at Aperfeiçoamento Em Periodontia by Universidade Federal de Minas Gerais (2000) . Currently is of Universidade Federal dos Vales do Jequitinhonha e Mucuri - Campus JK, of Universidade Federal dos Vales do Jequitinhonha e Mucuri - Campus JK, Revisor de periódico of Revista Periodontia, Revisor de periódico of Revista Saúde.com (Online), Revisor de periódico of Revista Dental Press de periodontia e implantologia, of University of Florida e Revisor de periódico of Journal of Indian Society of Periodontology. Has experience in the area of Odontology , with emphasis on Periodontia. Focused, mainly, in the subjects: regeneração periodontal, cemento, lesão de furca grau III, cães. 
Enilson Antonio Sallum, School of Dentistry at Piracicaba
Possui graduação em Odontologia pela Universidade Estadual de Campinas(1990), especialização em Periodontia pela Universidade Estadual de Campinas(1996), mestrado em Biologia Patologia Buco Dental pela Universidade Estadual de Campinas(1993), doutorado em Clínica Odontológica pela Universidade Estadual de Campinas(1996) e pós-doutorado pela University of Texas - Houston(1999). 
Antonio Wilson Sallum, School of Dentistry at Piracicaba
Possui graduação em Odontologia pela Universidade Estadual de Campinas(1967), especialização em Periodontia pela Universidade Estadual de Campinas(1980), especialização em Endodontia pela Universidade Estadual de Campinas(1980) e doutorado em Ciências Periodontia pela Universidade Estadual de Campinas(1973). Atualmente é professor titular da Universidade Estadual de Campinas. Tem experiência na área de Odontologia, com ênfase em Clínica Odontológica. 
Márcio Zaffalon Casati, School of Dentistry at Piracicaba
Possui graduação em Odontologia pela Universidade Estadual de Campinas (1995), mestrado em Clínica Odontológica pela Universidade Estadual de Campinas (1999) e doutorado em Clínica Odontológica pela Universidade Estadual de Campinas (2001). Atualmente é professor associado da Universidade Estadual de Campinas e professor titular da Universidade Paulista.
Sérgio Toledo, School of Dentistry at Piracicaba
Possui graduação em Ciências Biológicas Modalidade Médica pela Universidade Federal de São Paulo (1995), mestrado, doutorado e pós-doutorado em Ciências Biológicas (Biologia Molecular) pela Universidade Federal de São Paulo (1998, 2002 e 2006, respectivamente), e pós-doutorado pelo Pacific Northwest Research Institute - University of Washington (2005). Atualmente é Professor Adjunto III do Departamento de Bioquímica da Universidade Federal de São Paulo.
Francisco Humberto Nociti Junior, School of Dentistry at Piracicaba
graduate at Odontologia from Pontifícia Universidade Católica de Campinas (1988), master's at Odontology from Universidade Estadual de Campinas (1994) and ph.d. at Clinical Odontology from Universidade Estadual de Campinas (1997). Has experience in Odontology, acting on the following subjects: doenças periodontais, regenerative procedures, titanium implants, smoking/adverse effects and osseointegration.

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Published
2015-11-17
How to Cite
Gonçalves, P. F., Sallum, E. A., Sallum, A. W., Casati, M. Z., Toledo, S., & Nociti Junior, F. H. (2015). Dental cementum reviewed: development, structure, composition, regeneration and potential functions. Brazilian Journal of Oral Sciences, 4(12), 651-658. https://doi.org/10.20396/bjos.v4i12.8641790
Section
Literature Reviews