Histopathology and ultrastructural features in mucous extravasation phenomenon: Report of a case
Keywords:Extravasation mucocele. Mucin. TEM. Ultrastructural. Contractile filaments
AbstractHistopathological and ultrastructural features of a case of pseudocyst extravastation mucocele lesion located in the lower lip of an 18 yearold Malaysian female is presented. Complete surgical excision of the lesion with associated minor salivary glands was done. The specimen was processed for routine histopathology and transmission electron microscopy (TEM) for ultrastructral studies. The lesion revealed pooling of mucin infiltrated with inflammatory cells and walled by a rim of granulation tissue. The underlying salivary lobules showed varying degrees of chronic sclerosing sialadenitis. Ultrastructural features revealed multiple membrane bound electron lucent mucus granules with varying diameter, duct cells with few microvilli. Desmosomes, tonofilaments and myoepithelial cells were prominent. There were also dilatation of the rough endoplasmic reticulum (RER) and presence of multiple electron dense granules
Bodner L, Tal H. Salivary gland cysts of the oral cavity: clinical observation and surgical management. Compendium 1991; 12: 150, 152, 154-6.
Harrison HD. Sublingual gland is origin of cervical extravasation mucocele.Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90: 404-5.
Mustapha Indra Z, Boucree Jr Stanley A: Mucocele of the upper lip: case reportof an uncommon presentation and its differential diagnosis. J Can Dent Assoc 2004; 70: 318-21
Azuma M, Tamatani T, Fukui K, et al: Proteolytic enzymes in salivary extravasation mucoceles. J Oral Pathol Med 1995; 24: 299-302.
Bermejo A, Aguirre JM, Lopez P, Saez MR. Superficial mucocele: report of 4 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88: 469-72.
Ellis GL, Auclair PL. Tumor-like conditions. In: Atlas of tumor pathology:tumors of the salivary glands. Washington (DC): Armed Forces Institute of Patholgy; 1995. p.411-40.
Greenberg MS. Salivary gland diseases. In Lynch MA, editor. burket’s oral medicine: diagnosis and treatment. Philadelphia: Lippincott-Reven Publishers; 1994. p.415-8.
Sapp JP, Evarsole LR, Wysocki GP. Salivary gland disorders. In: Ducan LL, editor. Comtemporary Oral and Maxillofacial pathology. Saint Louis: Mosby Year-Book; 1997. p.19-26.
Wood NK, Goaz PW, Sawyer DR. Intraoral brownish, bluish, or black conditions. In: Ducan LL, editor. Differential Diagnosis of Oral and Maxillofacial Lesions. Saint Louis: Mosby-Year Book; 1997. p.82-208.
Selim MA. Mucus cyst. EMedicine; 2001. Available form: URL: http://www.emedicine.com/derm/topic274.htm .
Regezi JA, Sciubba JJ. Salivary gland diseases. In: Oral pathology:clinical pathologic correlations. Philadelphia: W.B. Saunders; 1989. p.225-83.
Ross M H, Romerll L.J, Kaye G.I. Digestive system I oral cavity and Pharynx. In: Histology a text and atlas.3rd ed. Baltimore: Willimas & Wilkins; 1995.
Cohen L. Mucoceles of the oral cavity. Oral Surg Oral Med Oral Pathol 1965; 19: 365-72.
Ellis GL, Auclair PL, Gnepp DR, editors. Obstructive disorders In: Surgical pathology of the salivary glands. Philadelphia: W.B. Saunders; 1991; p.26-38.
Yamasoba T, Tayama N, Syoji M, Fukuta M: Clinicostatistical study of lower lip mucoceles. Head Neck 1990; 12: 316-20.
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