Banner Portal
Ethnomedicine: use in dental caries


Dental caries. Herbal. Plants. Ethnomedicine

How to Cite

Singh J, Kumar A, Budhiraja S, Hooda A. Ethnomedicine: use in dental caries. Braz. J. Oral Sci. [Internet]. 2016 Jan. 21 [cited 2024 Apr. 15];6(21):1308-12. Available from:


Ubiquitousness and increasing prevalence of dental caries makes it one of the most important problems in public health. Due to high cost and lack of resources at primary levels prevention is better in dental caries. Since the origin is related to bacteria, antibacterial is mainstay of treatment. Lack of high efficacy with antibacterial agents, unwanted effects and resistance to these agents are drawing attention of scientists to search for new and better drugs. Plants products are currently gaining attention for treatment of various ailments. Although, these has been exploited for various oral ailments this article describes use of plants products for prevention and cure of dental caries.


Gibbons RJ, Van Houte J. Bacterial adherence in oral microbial ecology. Ann Rev Microbial. 1975; 29: 1-44.

Loesche WJ. Role of Streptococcus mutans in human dental decay. Mecrobiol Rev. 1986; 50: 353-80.

Chen LI, Lili MA, Heepark NO, Shi W. Cariogenic actinomyces identified with a â-glucosidase dependent green colour reaction to Gardania Jasminoides extract. J Clin Microbiol. 2001; 39: 3009-12.

Yanagida A, Kanda T, Tanabe M, Matsndaira F, Cordeiro JGO. Inhibitory effects of apple polyphenols and related compounds on cariogenic factors of mutans Streptococci. J Agric Food Chem. 2000; 48: 5666-71.

Raamsdonk M, Mei HC, Soet JJ, Busscher HJ, Graff J. Effect of polyclonal and monoclonal antibodies on surface properties of Streptococcus sorbrinus. Infec Immun. 1995; 63: 1698-1702.

Kubo I, Muroi H, Himejima M. Antimicrobial activity against Streptococcus mutans of mate tea flavor components. J Agric Food Chem. 1992; 40: 245-8.

Venditti M, Baiocchi P, Santini C, Brandimarte C, Serra P, Gentile G, et al. Antimicrobial susceptibilities of streptococcus species that cause septicemia in neutropenic patients. Antimicrob Agents Chemother. 1989; 33: 580-2.

Jonathan EK, Anna KJ, Johannes VS. Zulu medicinal plants with antibacterial activity. J Ethnopharmacol. 2000; 69: 241-6.

Saeki Y, Ito Y, Okuda K. Antimicrobial action of natural substances on oral bacteria. Bull Tokyo Dent Col. 1989; 30: 129-35.

Sakanaka S, Kim M, Taniguchi M, Yamamoto T. Antibacterial substances in Japanese green tea extract against Streptococcus mutans, a cariogenic bacterium. Agric Biochem. 1989; 53: 2307- 11.

Joann LD, Sigmund SS. Comparative in vitro activity of Sanguinariane against oral microbial isolates. Antimicrob Agents Chemother. 1985; 27: 663-5.

Rao K. Materials for the database of medicinal plants. Bangalore: Karnataka State Council for Science and Technology; 2000.

Chopra RN, Chopra IC, Handa KL, Kapur LD. Chopra’s indigenous drugs of India. 2nd ed. Calcutta: UN Dhur and Sons; 1958.

Vanka A, Tandon S, Rao SR, Udupa N. The effect of indigenous neem (Azadirachta Indica) mouth wash on Streptococcus mutans and lactobacilli growth. Ind J Dent Res. 2001; 12: 133-44.

Hebbar SS, Harsha VH, Shripathi V, Hegde GR. Ethnomedicine of Dharwad district in Karnataka India. Plants used in oral health care. J Ethnopharmacol. 2004; 94: 261-6.

Namba T, Tsunezuka M, Hattori M. Dental caries prevention by traditional Chinese medicines. Planta Med. 1982; 44: 400-6.

Kohda H, Kozai K, Nagasaka N, Miyake Y, Suginaka H, Hidaka K. Prevention of dental caries by oriental folk medicines- active principles of Zizyphi fructus for inhibition of insoluble glucan formation by cariogenic bacterium Streptococcus mutans. Planta Med. 1986; 2: 119-20.

Toukairin T, Uchino K, Iwamoto M, Murakami S, Tatebayashi T, Ogawara H, et al. New polyphenolic 5-nucleotidase inhibitor isolated from the wine grape “Koshu” and their biological effects. Chem Pharm Bull (Tokyo). 1991; 39: 1480-3.

Gazi M, Davies TJ, AL-Bagiah N, Cox SW. The immediate and medium term effects of Meswak on the composition of mixed saliva. J Clin Periodontal. 1992; 19: 113-7.

Tsuchiya H, Sato M, Linuma M, Yokoyama J, Chyama M, Tanaka T, et al. Inhibition of the growth of cariogenic bacteria in vitro by plant flavanones. Experientia. 1994; 50: 846-9.

Osawa K, Yasuda H, Morita H, Takeya K, Itokawa H. Eucalyptone from Eucalyptus globules. Phytochemistry. 1995; 40: 183-4.

Sato M, Fujiwara S, Tsuchiya H, Fujii T, Linuma M, Tosa H, et al. Flavones with antibacterial activity against cariogenic bacteria. J Ethnopharmacology. 1996; 54: 171-6.

Kim JH. Antibacterial action of onion (Allium cepa) extracts against oral pathogenic bacteria. J Nihon Univ Sch Dent. 1997; 39: 136-41.

Didry N, Dubreuil L, Trotin F, Pinkas M. Antimicrobial activity of aerial parts of Drosera peltata smith on oral bacteria. J Ethnopharmacology. 1998; 60: 91-6.

Jagtap AG, Karkera SG. Extract of Juglandaceae regia inhibits growth, in vitro adherence, acid production and aggregation of Streptococcus mutans. J Pharm Pharmacol. 2000; 52: 235-42.

Katsura H, Tsukiyama RI, Suzuki A, Kobayashi M. In vitro antimicrobial activity of Bakuchiol against oral microorganism. Antimicrobial Agents Chemother. 2001; 45: 3009-13.

Wongkham S, Laupallarakasaem P, Pienlhaweechai K, Areejitranusorm P, Wongkham C, Techanitiswad T. Antimicrobial activity of Streblus asper leaf extract. Phytother Res. 2001; 15: 119-21.

Yamamoto H, Ogawa T. Antimicrobial activity of perilla seed polyphenols against oral pathogenic bacteria. Biosci Biotechnol Biochem 2002; 66: 921-4.

Addai FK, Nuamah IK, Parkins GE. Brief chewing of Garcinia manii stick reverses reduced saliva pH after a glucose rinse. Med Sci Monit 2002; 8: CR746-50.

Park KM, You JS, Lee HY, Baek NI, Hwang JK. Kuwanon G: An antibacterial agent from the root bark of Morus alba against oral pathogens. J Ethnopharmacol 2003; 84: 181-5.

Porchezhian E, Dobrival RM. An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents. Pharmazie 2003; 58: 5-12.

Sato M, Tanaka H, Fujiwara S, Hirata M, Yamaguchi R, Etoh H, Tokuda C. Antibacterial property of isoflavonoids isolated from Erythrina variegata against cariogenic oral bacteria. Phytomedicine 2003; 10: 427-33.

Lee MJ, Lambert JD, Prabhu S, Meng X, Lu H, Haliakal P, et al. Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract. Cancer Epidemiol Biomarkers Pre 2004; 13: 132-7.

Xiao Y, Liu TJ, Huang ZW, Zhou XD, Li JY. The effect of natural medicine on adherence of Streptococcus mutans to salivary acquired pellicle. Sichuan Da Xue Xue Baoxue Ban. 2004; 35: 687-9.

Trongtokit Y, Rongsriyyam Y, Komilamisra N, Krisackphong P, Apiwathnasorn C. Laboratory and field trial of developing medicinal local Thai plant products against four species of mosquito vectors. Southeast Asian J Trop Med Public Health 2004; 35: 325-33.

Hwang JK, Chung JY, Baek NI, Park JH. Isopanduratin A from Kaempferia pandurata an active antibacterial agent against cariogenic Streptococcus mutans. Int J Antimicrob Agents 2004; 23: 377-81.

Uzel A, Sorkun K, Oncag O, Cogulu D, Gencav O, Salih B. Chemical compositions and antimicrobial activities of four different Anatolian propolis samples. Microbial Res 2005; 160: 189-95.

Leitao DP, Filho AA, Polizello AC, Bastos JK, Spadaro AC. Comparative evaluation of in vitro effects of Brazilian green propolis and Baccharis dracunculifolia extracts on cariogenic factors of Streptococcus mutans. Biol Pharm Bull 2004; 27: 1834-9.

Yatsuda R, Rosalen PL, Silva F, Fujita MG, Cury JA, Rehder VG, et al. Antimicrobial activity of compounds isolated from Mikania laevigata and M. glomerata on oral pathogens. Caries Res 2005; 39: 312.

The Brazilian Journal of Oral Sciences uses the Creative Commons license (CC), thus preserving the integrity of the articles in an open access environment.


Download data is not yet available.