Obesity and periodontal disease: why suggest such relationship? An overview

Keywords: Obesity. Periodontitis. Insulin resistance. Hyperlipidemia

Abstract

Obesity is a chronic condition that has social and economic implications for public health. It can be associated with periodontal disease since the metabolic alterations observed in that condition could have some influence in immunity. The elevated levels of lipid and glucose can be associated with periodontal disease, contributing to an exacerbated host inflammatory response, alterations in neutrophil function, and with the inhibition of macrophage growth factors, reducing tissuehealing capacity. In this way, obese individuals could have higher chances of undergoing tissue destruction in the presence of periodontal infection. On the other hand, periodontitis may be involved in alterations of lipid metabolism, since gram-negative bacteria could promote a rise in cholesterol and triglyceride levels due to chronic exposure to low levels of LPS in circulating blood, leading to the production of cytokines, which could initiate the production of lipoproteins by the liver. The objective was to review the literature about obesity and periodontal disease and provide a better understanding of their relationship.

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Author Biographies

Beatriz de Brito Bezerra, student
Graduada em Odontologia pela Universidade Federal do Ceará. Possui Mestrado e Doutorado em Clínica Odontológica, área de concentração Periodontia, obtidos em 2007 e 2010, pela FOP-UNICAMP. Realizou Doutorado Sanduiche (2009-2010) na New Jersey Dental School (UMDNJ). Suas linhas de pesquisa incluem periodontite experimental, regeneracao/reparo ossea(o), influencia de alteracoes sistemicas sobre reparo dos tecidos periodontais.
Enilson Antônio Sallum, State University of Campinas
Possui graduação em Odontologia pela Universidade Estadual de Campinas(1990), especialização em Periodontia pela Universidade Estadual de Campinas(1996), mestrado em Biologia Patologia Buco Dental pela Universidade Estadual de Campinas(1993), doutorado em Clínica Odontológica pela Universidade Estadual de Campinas(1996) e pós-doutorado pela University of Texas - Houston(1999). 
Antônio Wilson Sallum, State University of Campinas
Possui graduação em Odontologia pela Universidade Estadual de Campinas(1967), especialização em Periodontia pela Universidade Estadual de Campinas(1980), especialização em Endodontia pela Universidade Estadual de Campinas(1980) e doutorado em Ciências Periodontia pela Universidade Estadual de Campinas(1973). 

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Published
2016-01-22
How to Cite
Bezerra, B. de B., Sallum, E. A., & Sallum, A. W. (2016). Obesity and periodontal disease: why suggest such relationship? An overview. Brazilian Journal of Oral Sciences, 6(23), 1420-1422. https://doi.org/10.20396/bjos.v6i23.8643004
Section
Literature Reviews

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