Epidemiological features of patients with nonsyndromic cleft lip and/or palate in Western Parana

Authors

  • Helenara Salvati Bertolossi Moreira Universidade Estadual do Oeste do Paraná – UNIOESTE, Department of Physiotherapy, Cascavel, PR, Brazil
  • Renato Assis Machado Universidade Estadual de Campinas – UNICAMP, Piracicaba Dental School, Department of Oral Diagnosis, Piracicaba, SP, Brazil
  • Sibele Nascimento de Aquino Universidade Federal de Juiz de Fora - UFJF, School of Dentistry, Area of Stomatology Clinic, Governador Valadares, MG, Brazil
  • Ana Lúcia Carrinho Ayroza Rangel Universidade Estadual do Oeste do Paraná – UNIOESTE, Department of Physiotherapy, Cascavel, PR, Brazil
  • Hercílio Martelli Júnior Universidade Estadual de Montes Claros – UNIMONTES, Dental School, Area of Stomatology Clinic, Montes Claros, MG, Brazil
  • Ricardo Della Coletta Universidade Estadual de Campinas – UNICAMP, Piracicaba Dental School, Department of Oral Diagnosis, Piracicaba, SP, Brazil

DOI:

https://doi.org/10.20396/bjos.v15i1.8647121

Keywords:

Cleft lip. Epidemiology. Risk factors.

Abstract

Aim: : To describe the clinical, demographic and environmental features associated with NSCL/P (nonsyndromic cleft lip and/or palate) patients born in western Parana state, Brazil. Methods: This cross-sectional, observational, retrospective study included 188 patients attended at the Association of Carriers of Cleft Lip and Palate - APOFILAB, Cascavel-Parana, between 2012 and 2014. Information on demographic characteristics, medical and dental histories and life style factors were obtained from records and personal interviews. Results: Among the 188 patients, cleft lip and palate (CLP) was the most frequent subtype (55.8%), followed by cleft lip only (CLO, 25.0%) and cleft palate only (CPO, 19.2%). Caucasian males were the most affected, although no differences among types of cleft were observed. The otorhinolaryngologic and respiratory alterations were the most frequent systemic alterations in NSCL/P patients, and more than 80% of the NSCL/P mothers reported no vitamin supplements during the first trimester of pregnancy. Conclusions: This study revealed that the prevalence of nonsyndromic oral cleft types in this cohort was quite similar to previously reported prevalence rates. Systemic alterations were identified among 23.4% of the patients and patients with CLP were the most affected. History of maternal exposition to environmental factors related to nonsyndromic oral clefts was frequent and most mothers reported no vitamin supplements during the pregnancy. This study highlights the importance of identifying systemic alterations and risk factors associated with NSCL/P in the Brazilian population for planning comprehensive strategies and integrated actions for the development of preventive programs and treatment.

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Author Biographies

Helenara Salvati Bertolossi Moreira, Universidade Estadual do Oeste do Paraná – UNIOESTE, Department of Physiotherapy, Cascavel, PR, Brazil

Graduação em Fisioterapia pela PUC- Pontifícia Universidade Católica do Paraná (1994), especialista em Traumato Ortopédia Funcional (2005) e Fisioterapia Aquática (2009). Mestrado em Ergonomia pelo Programa de Pós Graduação em Engenharia de Produção da UFSC-Universidade Federal de Santa Catarina (2002). Doutora em Estomatopatologia pelo Programa de Pós Graduação da Faculdade de Odontologia da Unicamp (2014).Professora titular da Universidade Estadual do Oeste do Paraná - UNIOESTE desde 2000. Atualmente ministra a disciplina de Fisioterapia Preventiva. Atua também na Fisioterapia Pediátrica em Neuropediatria e nas doenças Neuromusculares da infância com formação no Conceito Neuroevolutivo Bobath(2004). 

Renato Assis Machado, Universidade Estadual de Campinas – UNICAMP, Piracicaba Dental School, Department of Oral Diagnosis, Piracicaba, SP, Brazil

Graduado em Odontologia pela Universidade José do Rosário Vellano - Unifenas (2012). Possui mestrado em Estomatopatologia pela Faculdade de Odontologia de Piracicaba, da Universidade Estadual de Campinas - FOP/Unicamp. Atualmente, é aluno de doutorado em Estomatopatologia pela FOP-Unicamp. Áreas de atuação: Estomatologia, Fissuras do lábio e/ou palato e doenças genéticas com ênfase em Malformações Craniofaciais.

 

Sibele Nascimento de Aquino, Universidade Federal de Juiz de Fora - UFJF, School of Dentistry, Area of Stomatology Clinic, Governador Valadares, MG, Brazil

Graduada em Odontologia, pela Universidade Estadual de Montes Claros/UNIMONTES. Possui Mestrado e Doutorado em Estomatopatologia (Faculdade de Odontologia de Piracicaba - FOP da Universidade Estadual de Campinas -UNICAMP). Atua nas áreas de Patologia Bucal, Malformações Craniofaciais,Doenças infecto-contagiosas com manifestação bucal, Lesões com envolvimento craniofacial e Epidemiologia. Foi professora do departamento de Medicina da Universidade Estadual de Montes Claros e professora das disciplinas de Patologia Bucal e Clínica de Diagnóstico Bucal das Faculdades Unidas do Norte de Minas. Atuou como membro permanente do Mestrado Profissional em Cuidado Primário em Saúde e membro colaborador do Programa de Pós Graduação em Ciências da Saúde da Universidade Estadual de Montes Claros. Orientadora de Mestrado e Co-orientadora de Doutorado. Atualmente é professora de Patologia Maxilofacial I, II e III, Semiologia e Propedêutica da Universidade Federal de Juiz de Fora e Gerente de Graduação do Campus Governador Valadares.

Ana Lúcia Carrinho Ayroza Rangel, Universidade Estadual do Oeste do Paraná – UNIOESTE, Department of Physiotherapy, Cascavel, PR, Brazil

Possui graduação em Odontologia pela Universidade de Taubaté (1998), Mestrado, (2001), Doutorado (2004) e Pós-doutorado (2007) em Estomatopatologia pela Universidade Estadual de Campinas (UNICAMP). Atualmente é Professora Associada da Universidade Estadual do Oeste do Paraná (UNIOESTE/Campus de Cascavel), docente dos Programas de Pós-graduação em Odontologia (UNIOESTE) e Estomatopatologia (FOP/UNICAMP). Atua nas áreas de Estomatologia e Patologia oral, com ênfase em histopatologia.

Hercílio Martelli Júnior, Universidade Estadual de Montes Claros – UNIMONTES, Dental School, Area of Stomatology Clinic, Montes Claros, MG, Brazil

É Professor Titular de Diagnóstico Bucal do Centro de Ciências Biológicas e da Saúde da Universidade Estadual de Montes Claros, Unimontes e Professor Permanente (Orientador de Mestrado e Doutorado) do Programa de Pós-Graduação em Ciências da Saúde e Cuidado Primário em Saúde da Universidade Estadual de Montes Claros. É Pró-Reitor de Pós-Graduação da Universidade Estadual de Montes Claros. Foi membro técnico da Câmara da Saúde - CDS - da Fundação de Amparo à Pesquisa do Estado de Minas Gerais - Fapemig, entre os anos de 2006 a 2010. Consultor técnico do Conselho Estadual de Educação e Consultor da Secretaria de Educação Superior do Ministério da Educação - SESu (Programa de Educação Tutorial - PET). Atua nas linhas de pesquisa em doenças genéticas, patologia bucal e epidemiologia. Presidiu, entre 2007-2010, o Comitê Institucional de Iniciação Científica - PIBIC-CNPq, da Unimontes e o Comitê do PIBIC-CNPq - Ações Afirmativas - de Iniciação Científica.

Ricardo Della Coletta, Universidade Estadual de Campinas – UNICAMP, Piracicaba Dental School, Department of Oral Diagnosis, Piracicaba, SP, Brazil

Possui graduação em Odontologia pela Universidade Estadual de Campinas (1994), mestrado em Biologia Patologia Buco-Dental pela Universidade Estadual de Campinas (1996) e doutorado em Biologia Patologia Buco-Dental pela Universidade Estadual de Campinas (1999) com estágio sanduíche de 12 meses na University of Maryland Dental School. Desenvolveu estágio de pós-doutoramento na School of Medicine, University of Colorado Denver. Atualmente é Professor Associado junto ao Departamento de Diagnóstico Oral, da Faculdade de Odontologia de Piracicaba, da Universidade Estadual de Campinas. Tem experiência na área de Odontologia, com ênfase em Patologia, Genética e Biologia Molecular, atuando principalmente nos seguintes temas: aumentos gengivais, câncer bucal, genes homeobox, fissuras lábio-palatinas e síndromes com envolvimento gengival.

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Published

2016-10-13

How to Cite

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Moreira HSB, Machado RA, Aquino SN de, Rangel ALCA, Martelli Júnior H, Della Coletta R. Epidemiological features of patients with nonsyndromic cleft lip and/or palate in Western Parana. Braz. J. Oral Sci. [Internet]. 2016 Oct. 13 [cited 2022 Aug. 17];15(1):39-44. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8647121

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