Abstract
Kaposi’s sarcoma (KS) is a locally aggressive multicentric mucocutaneous malignant neoplasm. The aim of this article is to report and discuss the immunohistochemical profile of a rare case of classic primary Oral Kaposi’s sarcoma presenting on the hard palate of a female patient which was non-HIV and was not immunocompromised.References
Barnes L, Eveson JW, Reichart P, Sidransky R, editors. World Health Organization Classification of Tumors. Pathology and Genetics Head and Neck Tumors. Lyon: IARC Press; 2005 [cited 2017 jun 5]. Available from: https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb9/BB9.pdf.
Fukumoto H, Kanno T, Hasegawa H, Katano H. Pathology of Kaposi's Sarcoma-Associated Herpesvirus Infection. Front Microbiol. 2011 Aug 25;2:175. doi: 10.3389/fmicb.2011.00175.
Fatahzadeh M, Schwartz RA. Oral Kaposi's sarcoma: a review and update. Int J Dermatol. 2013;52(6):666-72. doi: 10.1111/j.1365-4632.2012.05758.x.
Dal Maso L, Polesel J, Ascoli V, Zambon P, Budroni M, Ferretti S, et al. Classic Kaposi's sarcoma in Italy, 1985-1998. Br J Cancer. 2005;92(1):188-93.
Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994;266(5192):1865-9.
Duus KM, Lentchitsky V, Wagenaar T, Grose C, Webster-Cyriaque J. Wild-type Kaposi's sarcoma-associated herpesvirus isolated from the oropharynx of immune-competent individuals has tropism for cultured oral epithelial cells. J Virol. 2004;78(8):4074-84.
Seleit I, Attia A, Maraee A, Samaka R, Bakry O, Eid E. Isolated Kaposi Sarcoma in two HIV negative patients. J Dermatol Case Rep. 2011;5(2):24-6. doi: 10.3315/jdcr.2011.1067.
Pantanowitz L, Khammissa RA, Lemmer J, Feller L. Oral HIV-associated Kaposi sarcoma. J Oral Pathol Med. 2013;42(3):201-7. doi: 10.1111/j.1600-0714.2012.01180.x.
Mohanna S, Bravo F, Ferrufino JC, Sanchez J, Gotuzzo E. Classic Kaposi's sarcoma presenting in the oral cavity of two HIV-negative Quechua patients. Med Oral Patol Oral Cir Bucal. 2007;12(5):E365-8.
Bottler T, Kuttenberger J, Hardt N, Oehen HP, Baltensperger M. Non-HIV-associated Kaposi's sarcoma of the tongue. Case report and review of the literature. Int J Oral Maxillofac Surg. 2007;36(12):1218-20.
Reis-Filho JS, Souto-Moura C, Lopes JM. Classic Kaposi's sarcoma of the tongue: case report with emphasis on the differential diagnosis. J Oral Maxillofac Surg. 2002;60(8):951-4.
Markopoulos AK, Papanayotou P, Trigonidis G. Kaposi's sarcoma of the oral cavity: case reports. Quintessence Int. 1994;25(6):415-8.
Gordon E, Searles GE, Markman S, Yazdi HM. Primary oral Kaposi's sarcoma of the hard palate. J Am Acad Dermatol. 1990;23(3 Pt 1):518-9.
Wild R, Balmer MC. Have we forgotten? Oral Manifestations of Kaposi's Sarcoma. Sex Transm Infect. 2015;91(5):345. doi: 10.1136/sextrans-2015-052116
Regezi JA, Sciubba JJ, JordanRCK. Oral Pathology: clinical Pathologic Correlations. 4th ed. Saunders; 2003. Cap. 4: Red-Blue Lesions. p.204.
Ordóñez NG. Immunohistochemical endothelial markers: a review. Adv Anat Pathol. 2012;19(5):281-95. doi: 10.1097/PAP.0b013e3182691c2a.
Bishop PW. An immunohistochemical vade mecum. 2007 [cited 2017 jun 5]. Available fom: www.e-immunohistochemistry.info.
Miettinen M, Wang ZF, Paetau A, Tan SH, Dobi A, Srivastava S, et al. ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma. Am J Surg Pathol. 2011;35(3):432-41. doi: 10.1097/PAS.0b013e318206b67b.
The Brazilian Journal of Oral Sciences uses the Creative Commons license (CC), thus preserving the integrity of the articles in an open access environment.