Oral health in patients with cystic fibrosis

Authors

  • Aline Cristina Gonçalves University of Campinas
  • Fernando Augusto Lima Marson University of Campinas
  • Regina Maria Holanda Mendonça Boldrini Children's Center
  • José Dirceu Ribeiro University of Campinas
  • Antônio Fernando Ribeiro University of Campinas
  • Carlos Emílio Levy University of Campinas

DOI:

https://doi.org/10.20396/bjos.v17i0.8653988

Keywords:

Cystic fibrosis. Dental caries. Periodontal index. Oral health. Dental plaque index.

Abstract

The oral health in patients with cystic fibrosis (CF) is not well studied. Aim: In this context, we describe the frequency of dental problems and performed the description of plaque index and gingival index in patients with CF. Methods: We performed a descriptive study about oral health enrolling 94 patients with CF. Results: The CF diagnosis was done considering the sweat test with chloride values ≥ 60 mmol/L. The permanent dentition was predominant in 57/94 (60.64%) patients with CF – 28/57 (49.12%) caries, 57/57 (100%) filled teeth and 1/57 (1.75%) missing tooth. Deciduous teeth occurred in 37/94 (39.36%) patients with CF – 22/37 (59.46%) carious, 29/37 (78.38%) exfoliated teeth, 20/37 (54.05%) filled teeth. Also, the plaque index and gingival index had scored less than one in many cases (≥ 50% of the cases). Conclusions: Patients with CF showed oral health problems with prevalence comparable to that of the normal population and low values in the plaque index and gingival index.

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Author Biographies

Aline Cristina Gonçalves, University of Campinas

Department of Pediatrics, University of Campinas, School of Medical Sciences.

Fernando Augusto Lima Marson, University of Campinas

Department of Pediatrics, University of Campinas, School of Medical Sciences.

Regina Maria Holanda Mendonça, Boldrini Children's Center

Boldrini Children's Center.

José Dirceu Ribeiro, University of Campinas

Department of Pediatrics, University of Campinas, School of Medical Sciences.

Antônio Fernando Ribeiro, University of Campinas

Department of Pediatrics, University of Campinas, School of Medical Sciences.

Carlos Emílio Levy, University of Campinas

Department of Clinical Pathology, University of Campinas, School of Medical Sciences.

References

Ferrazzano GF, Orlando S, Sangianantoni G, Cantile T, Ingenito A. Dental and periodontal health status in children affected by cystic fibrosis in a southern Italian region. Eur J Paediatr Dent. 2009 Jun;10(2):65-8.

Ferrazzano GF, Sangianantoni G, Cantile T, Amato I, Orlando S, Ingenito A. Dental enamel defects in Italian children with cystic fibrosis: an observational study. Community Dent Health. 2012 Mar;29(1):106-9.

Narang A, Maguire A, Nunn JH, Bush A. Oral health and related factors in cystic fibrosis and other chronic respiratory disorders. Arch Dis Child. 2003 Aug;88(8):702-7.

Peker S, Kargul B, Tanboga I, Tunali-Akbay T, Yarat A, Karakoc F, et al. Oral health and related factors in a group of children with cystic fibrosis in Istanbul, Turkey. Niger J Clin Pract. 2015 Jan-Feb;18(1):56-60. doi: 10.4103/1119-3077.146980.

Sarvas EW, Huebner CE, Scott JM, Aps JK, Chi DL. Dental utilization for Medicaid-enrolled children with cystic fibrosis. Spec Care Dentist. 2016 Nov;36(6):315-320. doi: 10.1111/scd.12193.

Clarkson J, O'Mullane D. A modified DDE Index for use in epidemiological studies of enamel defects. J Dent Res. 1989 Mar;68(3):445-50.

Faria AG, Marson FAL, Gomez CCS, Servidoni MF, Ribeiro AF, Ribeiro JD. Thirty Years of Sweat Chloride Testing at One Referral Center. Front Pediatr. 2017 Oct 26;5:222. doi: 10.3389/fped.2017.00222.

Farrell PM, White TB, Ren CL, Hempstead SE, Accurso F, Derichs N, et al. Diagnosis of Cystic Fibrosis: Consensus Guidelines from the Cystic Fibrosis Foundation. J Pediatr. 2017 Feb;181S:S4-S15.e1. doi: 10.1016/j.jpeds.2016.09.064.

Silness J, Loe H. Periodontal disease in pregnancy. ii. correlation between oral hygiene and periodontal condtion. Acta Odontol Scand. 1964 Feb;22:121-35.

Löe H. The Gingival Index, the Plaque Index and the Retention Index Systems. J Periodontol. 1967 Nov-Dec;38(6):Suppl:610-6.

Harrington N, Barry PJ, Barry SM. Dental treatment for people with cystic fibrosis. Eur Arch Paediatr Dent. 2016 Jun;17(3):195-203. doi: 10.1007/s40368-016-0229-9.

Primosch RE, Brearley L. Dental caries experience in patients with cystic fibrosis. J Dent Res. 197888;57:150.

Primosch RE. Tetracycline discoloration, enamel defects, and dental caries in patients with cystic fibrosis. Oral Surg Oral Med Oral Pathol. 1980 Oct;50(4):301-8.

Kinirons MJ. Dental health of patients suffering from cystic fibrosis in Northern Ireland. Community Dent Health. 1989 Jun;6(2):113-20.

Aps JK, Van Maele GO, Martens LC. Caries experience and oral cleanliness in cystic fibrosis homozygotes and heterozygotes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 May;93(5):560-3.

Chi DL. Dental caries prevalence in children and adolescents with cystic fibrosis: a qualitative systematic review and recommendations for future research. Int J Paediatr Dent. 2013 Sep;23(5):376-86. doi: 10.1111/ipd.12042.

O'Keefe E. Are children and adolescents with cystic fibrosis at lower risk of caries? Evid Based Dent. 2014 Jun;15(2):46-7. doi: 10.1038/sj.ebd.6401024.

Jagels AE, Sweeney EA. Oral health of patients with cystic fibrosis and their siblings. J Dent Res. 1976 Nov-Dec;55(6):991-6.

Peker S, Mete S, Gokdemir Y, Karadag B, Kargul B. Related factors of dental caries and molar incisor hypomineralisation in a group of children with cystic fibrosis. Eur Arch Paediatr Dent. 2014 Aug;15(4):275-80. doi: 10.1007/s40368-014-0112-5.

Aps JK, Van Maele GO, Claeys G, Martens LC. Mutans streptococci, lactobacilli and caries experience in cystic fibrosis homozygotes, heterozygotes and healthy controls. Caries Res. 2001 Nov-Dec;35(6):407-11.

Martens LC, Aps JKM, Van Maele GOG. Is oral health at risk in people with cystic fibrosis? Eur J Paediat Dent. 2001 Mar;2:21-7.

Kinirons MJ. Increased salivary buffering in association with a low caries experience in children suffering from cystic fibrosis. J Dent Res. 1983 Jul;62(7):815-7.

Hirsch R. Periodontal healing and bone regeneration in response to azithromycin. Aust Dent J. 2010 Jun;55(2):193-9. doi: 10.1111/j.1834-7819.2010.01227.x.

Sweeney EA, Shaw JH. The effect of dietary pancreatin supplements on dental caries and on the composition of saliva in caries-susceptible rats. J Dent Res. 1965 Sep-Oct;44(5):973-6.

Faran Ali SM, Tanwir F. Oral microbial habitat a dynamic entity. J Oral Biol Craniofac Res. 2012 Sep-Dec;2(3):181-7. doi: 10.1016/j.jobcr.2012.07.001.

Marques SC, Rezende JDGOS, Alves LADF, Silva BC, Alves E, De Abreu LR, et al. Formation of biofilms by Staphylococcus aureus on stainless steel and glass surfaces and its resistance to some selected chemical sanitizers. Bra J Microbiol. 2007 Jul/Sep;38(3):538-43. doi: 10.1590/S1517-83822007000300029.

Sui W, Boyd C, Wright JT. Altered pH regulation during enamel development in the cystic fibrosis mouse incisor. J Dent Res. 2003 May;82(5):388-92.

Wright JT, Kiefer CL, Hall KI, Grubb BR. Abnormal enamel development in a cystic fibrosis transgenic mouse model. J Dent Res. 1996 Apr;75(4):966-73.

Arquitt CK, Boyd C, Wright JT. Cystic fibrosis transmembrane regulator gene (CFTR) is associated with abnormal enamel formation. J Dent Res. 2002 Jul;81(7):492-6.

Duan X. Ion channels, channelopathies, and tooth formation. J Dent Res. 2014 Feb;93(2):117-25. doi: 10.1177/0022034513507066.

Azevedo TD, Feijó GC, Bezerra AC. Presence of developmental defects of enamel in cystic fibrosis patients. J Dent Child (Chic). 2006 Sep-Dec;73(3):159-63

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Published

2018-11-14

How to Cite

1.
Gonçalves AC, Marson FAL, Mendonça RMH, Ribeiro JD, Ribeiro AF, Levy CE. Oral health in patients with cystic fibrosis. Braz. J. Oral Sci. [Internet]. 2018 Nov. 14 [cited 2022 Aug. 10];17:e18160. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8653988