Association between hypertelorism and nonsyndromic oral clefts

Authors

  • Luciano Sólia Nasser State University of Montes Claros
  • Letízia Monteiro de Barros José do Rosário Vellano University
  • Daniella Reis Barbosa Martelli State University of Montes Claros
  • João Vitor Quadros Tonelli State University of Montes Claros
  • Mário Sérgio Oliveira Swerts State University of Montes Claros
  • Hercílio Martelli Júnior State University of Montes Claros

Keywords:

Letter to the editor.

Abstract

Hypertelorism is characterized by the increased distance between the orbits, measured from the most medial portion of its inner walls. It represents a signal found in sev eral craniofacial defects, and oral clefts. Nonsyndromic oral clefts (NOC) are the most common orofacial birth defect, occurring in 1 in 500-2,500 live births worldwide. NOC is caused by a complex interplay between environ mental exposures and genetic factors.

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Author Biographies

Luciano Sólia Nasser, State University of Montes Claros

Health Science Program - State University of Montes Claros.

Letízia Monteiro de Barros, José do Rosário Vellano University

Center for the Rehabilitation of Craniofacial Anomalies - José do Rosário Vellano University.

Daniella Reis Barbosa Martelli, State University of Montes Claros

Health Science Program - State University of Montes Claros.

João Vitor Quadros Tonelli, State University of Montes Claros

Dental School - State University of Montes Claros.

Mário Sérgio Oliveira Swerts, State University of Montes Claros

Health Science Program - State University of Montes Claros.

Hercílio Martelli Júnior, State University of Montes Claros

Health Science Program - State University of Montes Claros.

References

Costaras M, Pruzansky S, Broadbent BH Jr. Bony interorbital distance (BIOD), head size, and level of the cribriform plate relative to orbital height: I. Normal standards for age and sex. J Craniofac Genet Dev Biol. 1982;2(1):5-18.

Tan ST, Mulliken JB. Hypertelorism: nosologic analysis of 90 patients. Plast Reconstr Surg. 1997 Feb;99(2):317-27.

Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet. 2011 Mar;12(3):167-78. doi: 10.1038/nrg2933.

Cohen MM, Richieri-Costa A, Guion-Almeida ML, Saavedra D. Hypertelorism: interorbital growth, measurements and pathogenetic considerations. J. Oral Maxillofac Surg. 1995 Dec;24(6):387-95.

Weinberg SM, Leslie EJ, Hecht JT, Wehby GL, Deleyiannis FWB, Moreno LM, et al. Hypertelorism and Orofacial Clefting Revisited: An Anthropometric Investigation. Cleft Palate Craniofac J. 2017 Nov;54(6):631-8. doi: 10.1597/15-256.

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Published

2018-11-26

How to Cite

1.
Nasser LS, Barros LM de, Martelli DRB, Tonelli JVQ, Swerts MSO, Martelli Júnior H. Association between hypertelorism and nonsyndromic oral clefts. Braz. J. Oral Sci. [Internet]. 2018 Nov. 26 [cited 2022 Dec. 6];17:e18287. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8654058

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Letter to the Editor

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