Association of metabolic syndrome with oral and systemic conditions in morbidly obese patients

  • Gerson Aparecido Foratori-Junior Bauru School of Dentistry, University of São Paulo
  • Francisco Juliherme Pires de Andrade Bauru School of Dentistry, University of São Paulo
  • Victor Mosquim Bauru School of Dentistry, University of São Paulo
  • Matheus de Carvalho Sales Peres Botucatu School of Medicine, University of State of São Paulo
  • Elinton Adami Chaim Faculty of Medical Sciences, State University of Campinas. Campinas
  • Silvia Helena de Carvalho Sales-Peres Bauru School of Dentistry, University of São Paulo https://orcid.org/0000-0003-3811-7899
Keywords: Obesity, Metabolic syndrome, Tooth loss, Cardiovascular diseases.

Abstract

Aim: This study aimed to evaluate oral and systemic conditions in morbidly obese patients with and without metabolic syndrome (MS) prior to bariatric surgery. Methods: One hundred patients were included and equally divided into two groups: G1 - with MS (n = 50) and G2 - without MS (n = 50). MS was diagnosed in patients presenting at least three of five signs: abdominal obesity, high triglyceride level, low high-density lipoprotein cholesterol (HDL-C) level, hypertension, and altered fasting glycemia. Variables analyzed included the patients’ age, sex, body mass index (BMI), waist-to-hip ratio (WHR), and number of missing teeth. Both BMI and WHR were used to evaluate the risk of developing cardiovascular disease (RCVD). Mann-Whitney, Chi-squared, t test, hierarchical multiple linear regression and binary logistic regression models were used in statistical analyses (p<0.05). Results: There were no group-wise differences in sex (p=0.631) and BMI (p=0.200); however, the WHR (p=0.009), age (p=0.0001), and number of missing teeth (p=0.0003) were higher in G1. Obese patients with MS who were candidates for bariatric surgery presented higher RCVD than obese patients without MS (p=0.019). Binary logistic regression revealed patient age [adjusted OR=1.05, 95% CI=1.00-1.11, p=0.042] and number of missing teeth [adjusted OR=1.17, 95% CI=1.04-1.31, p=0.013] to be significant predictors of MS. Conclusion: Morbidly obese patients with MS had worse oral and systemic conditions than those without MS, regarding WHR, RCDV and number of missing teeth.

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Author Biographies

Gerson Aparecido Foratori-Junior, Bauru School of Dentistry, University of São Paulo
Department of Pediatric Dentistry, Orthodontics and Public Health
Francisco Juliherme Pires de Andrade, Bauru School of Dentistry, University of São Paulo
Department of Pediatric Dentistry, Orthodontics and Public Health
Victor Mosquim, Bauru School of Dentistry, University of São Paulo
Department of Operative Dentistry, Endodontics and Dental Materials.
Matheus de Carvalho Sales Peres, Botucatu School of Medicine, University of State of São Paulo
Department of General Surgery
Elinton Adami Chaim, Faculty of Medical Sciences, State University of Campinas. Campinas
Department of Surgery
Silvia Helena de Carvalho Sales-Peres, Bauru School of Dentistry, University of São Paulo
Department of Pediatric Dentistry, Orthodontics and Public Health

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Published
2019-04-25
How to Cite
Foratori-Junior, G. A., Andrade, F. J. P. de, Mosquim, V., Peres, M. de C. S., Chaim, E. A., & Sales-Peres, S. H. de C. (2019). Association of metabolic syndrome with oral and systemic conditions in morbidly obese patients. Brazilian Journal of Oral Sciences, 18, e191484. https://doi.org/10.20396/bjos.v18i0.8655299