Impact of radiotherapy on the bond strength of different adhesive systems to human dentin

one-year in vitro evaluation

  • Renally Bezerra Wanderley Lima Faculty of Nova Esperança
  • Maria Luiza Pontual Federal University of Pernambuco
  • Venâncio Fernandes Dantas Federal University of Paraíba
  • Sônia Saeger Meireles Federal University of Paraíba
  • Ana Karina Maciel Andrade Federal University of Paraíba
  • Rosângela Marques Duarte Federal University of Paraíba
Keywords: Dentin, Tensile strength, Radiotherapy, Head and neck neoplasms.


Aim: The aim of this study is to evaluate the effect of radiotherapy on the bond strength of resin-based composite restorations to dentin, performed either 24 h or 1 year before or after radiation. Methods: Ninety-six posterior teeth were randomly distributed into the following groups: IB (n = 16), irradiated teeth were restored 1 year after x-ray application; NB (n = 16), not irradiated teeth were stored for 1 year and then restored. IA (n = 32), teeth were restored and irradiated at 24 h or 1 year after the restoration. NA (n = 32), teeth were restored, not irradiated, and tested as IA. Eight samples from each group were randomly assigned to either the three-step or two-step etch-and rinse adhesive system procedure. The irradiated specimens were subjected to 60 Gy of x-ray radiation fractionally. The restored teeth were vertically sectioned, and 1-mm2 resin–dentin sticks were obtained and submitted to the microtensile bond strength test. The bond strength data were analyzed by two-way analysis of variance (ANOVA) followed by Tukey’s test (p < 0.05). Failure modes were examined by optical microscopy and scanning electron microscopy. Results: The IB group showed lower bond strength values compared to the NB group. The bond strength values between the adhesive systems were not statistically different. Conclusion: The application of radiation dose decreased the bond strength of the adhesive restorations to dentin when the bonding procedure was conducted 1 year after in vitro radiotherapy.


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Author Biographies

Renally Bezerra Wanderley Lima, Faculty of Nova Esperança

Department of Restorative Dentistry, Faculty of Nova Esperança , PB, Brazil.

Maria Luiza Pontual, Federal University of Pernambuco

Department of Clinic Dentistry, Federal University of Pernambuco, PE, Brazil.

Venâncio Fernandes Dantas, Federal University of Paraíba

Department of Restorative Dentistry, Federal University of Paraíba, PB, Brazil.

Sônia Saeger Meireles, Federal University of Paraíba

Department of Restorative Dentistry, Federal University of Paraíba, PB, Brazil.

Ana Karina Maciel Andrade, Federal University of Paraíba

Department of Restorative Dentistry, Federal University of Paraíba, PB, Brazil.

Rosângela Marques Duarte, Federal University of Paraíba

Department of Restorative Dentistry, Federal University of Paraíba, PB, Brazil.


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How to Cite
Lima, R. B. W., Pontual, M. L., Dantas, V. F., Meireles, S. S., Andrade, A. K. M., & Duarte, R. M. (2019). Impact of radiotherapy on the bond strength of different adhesive systems to human dentin. Brazilian Journal of Oral Sciences, 18, e191638.