Keywords
Tensile strength
Radiotherapy
Head and neck neoplasms.
How to Cite
Abstract
Aim: The aim of this study is to evaluate the effect of radiotherapy on the bond strength of resin-based composite restorations to dentin, performed either 24 h or 1 year before or after radiation. Methods: Ninety-six posterior teeth were randomly distributed into the following groups: IB (n = 16), irradiated teeth were restored 1 year after x-ray application; NB (n = 16), not irradiated teeth were stored for 1 year and then restored. IA (n = 32), teeth were restored and irradiated at 24 h or 1 year after the restoration. NA (n = 32), teeth were restored, not irradiated, and tested as IA. Eight samples from each group were randomly assigned to either the three-step or two-step etch-and rinse adhesive system procedure. The irradiated specimens were subjected to 60 Gy of x-ray radiation fractionally. The restored teeth were vertically sectioned, and 1-mm2 resin–dentin sticks were obtained and submitted to the microtensile bond strength test. The bond strength data were analyzed by two-way analysis of variance (ANOVA) followed by Tukey’s test (p < 0.05). Failure modes were examined by optical microscopy and scanning electron microscopy. Results: The IB group showed lower bond strength values compared to the NB group. The bond strength values between the adhesive systems were not statistically different. Conclusion: The application of radiation dose decreased the bond strength of the adhesive restorations to dentin when the bonding procedure was conducted 1 year after in vitro radiotherapy.
References
Al-Nawas B, Al-Nawas K, Kunkel M, Grötz KA. Quantifying radioxerostomia: salivary flow rate, examiner’s score, and quality of life questionnaire. Strahlenther Onkol. 2006 Jun;182(6):336-41.
Sulaiman F, Huryn JM, Zlotolow IM. Dental extractions in the irradiated head and neck patient: a retrospective analysis ofmemorial sloan-kettering cancer center protocols, criteria, and results. Br J Oral Maxillofac Surg. 2003 Oct;61(10):1123-31.
Beumer J, Curtis ThA, Marunick MT. Maxillofacial rehabilitation, prosthodontic and surgical considerations. Saint Louis: Medico Dental Media International; 1996. p.43-71.
Kielbassa AM, Hinkelbein W, Hellwig E, Meyer-Lückel H. Radiation-related damage to dentition. Lancet Oncol. 2006 Apr;7(4):326-35.
Walker MP, Wichman B, Cheng A-L, Coster J, Williams KB. Impact of radiotherapy dose on dentition breakdown in head and neck cancer patients. Pract Radiat Oncol. 2011;1(3):142-8.
Galetti R, Santos-Silva AR, Antunes AN, Alves FA, Lopes MA, de Goes MF. Radiotherapy does not impair dentin adhesive properties in head and neck cancer patients. Clin Oral Investig. 2014 Sep;18(7):1771-8. doi: 10.1007/s00784-013-1155-4.
Goncalves LM, Palma-Dibb RG, Paula-Silva FW, Oliveira HF, Nelson-Filho P, Silva LA et al. Radiation therapy alters microhardness and microstructure of enamel and dentin of permanent human teeth. J Dent. 2014 Aug;42(8):986-92. doi: 10.1016/j.jdent.2014.05.011.
Davis WB. Reduction in dentin wear resistance by irradiation and effects of storage in aqueous media. J Dent Res. 1975 Sep-Oct;54(5):1078-81.
Franzel W, Gerlach R, Hein HJ, Schaller HG. Effect of tumor therapeutic ir- radiation on the mechanical properties of teeth tissue. Z Med Phys.2006;16(2):148-54.
Kielbassa AM, Beetz I, Schendera A, Hellwig E. Irradiation effects on micro- hardness of fluoridated and non-fluoridated bovine dentin. Eur J Oral Sci. 1997 Oct;105(5 Pt 1):444-7.
Thiagarajan G, Vizcarra B, Bodapudi V, Reed R, Seyedmahmoud R, Wang Y, et al. Stress analysis of irradiated human tooth enamel using finite element methods. Comput Methods Biomech Biomed Engin. 2017 Nov;20(14):1533-42. doi: 10.1080/10255842.2017.1383401.
Lu H, Zhao Q, Guo J, Zeng B, Yu X, Yu D, et al. Direct radiation-induced effects on dental hard tissue. Radiat Oncol. 2019 Jan 11;14(1):5. doi: 10.1186/s13014-019-1208-1.
Marangoni-Lopes L, Rovai-Pavan G, Steiner-Oliveira C, Nobre-Dos-Santos M. Radiotherapy Reduces Microhardness and Mineral and Organic Composition, and Changes the Morphology of Primary Teeth: An in vitro Study. Caries Res. 2019;53(3):296-304. doi: 10.1159/000493099.
Grötz KA, Duschner H, Kutzner J, Thelen M, Wagner W. [New evidence for the etiology of the so-called radiation caries. Proof for direct radiogenic damage of the dento-enamel junction]. Strahlenther Onkol. 1997 Dec;173(12):668-76. German.
Fisher BV, Morgan RE, Phillips GO, Wardale HW. Radiation damage in calcium phosphates and collagen: an interpretation of ESR spectra. Radiat Res. 1971 May;46(2):229-35.
Cheung DT, Perelman N, Tong D, Nimni ME. The effect of gamma-irradiation on collagen molecules, isolated alpha-chains, and crosslinked native fibers. J Biomed Mater Res. 1990 May;24(5):581-9.
Odlum O. Preventive resins in the management of radiation- induced xerostomia complications. J Esthet Dent. 1991 Nov-Dec;3(6):227-9.
Mcomb D, Erickson RL, Maxymiw WG, Wood RE. A clinical comparison of glass ionomer, resin modified glass ionomer and resin composites restorations in the treatment of cervical caries in xerostomic head and neck radiation patients. Oper Dent. 2002 Sep-Oct;27(5):430-7.
Naves LZ, Novais VR, Armstrong SR, Correr-Sobrinho L, Soares CJ. Effect of gamma radiation on bonding to human enamel and dentin. Support Care Cancer. 2012 Nov;20(11):2873-8. doi: 10.1007/s00520-012-1414-y.
Bernard C, Villat C, Abouelleil H, Gustin MP, Grosgogeat B. Tensile Bond Strengths of Two Adhesives on Irradiated and Nonirradiated Human Dentin. Biomed Res Int. 2015;2015:798972. doi: 10.1155/2015/798972.
Rodrigues RB, Soares CJ, Simamoto Junior PC, Lara VC, Arana-Chavez VE, Novais VR. Influence of radiotherapy on the dentin properties and bond strength. Clin Oral Investig. 2018 Mar;22(2):875-883. doi: 10.1007/s00784-017-2165-4.
Açil Y, Springer I, Niehoff P, Gabling V, Warnke P, Açmaz S et al. Proof of Direct Radiogenic Destruction of Collagen in Vitro. Strahlenther Onkol. 2007 Jul;183(7):374-9.
Mellara TS, Palma-Dibb RG, Oliveira HF, Paula-Silva FWG, Nelson-Filho F, Silva RAB et al. The effect of radiation therapy on the mechanical and morphological properties of the enamel and dentin of deciduous teeth – an in vitro study. Radiation Oncology. 2014 Jan 22;9:30. doi: 10.1186/1748-717X-9-30.
Cole T, Silver AS. Production of hydrogen atoms in teeth by X-irradiation. Nature. 1963 Nov 16;200:700-1.
Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, et al. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials. 2007 Sep;28(26):3757-85.
Madrid Troconis CC, Santos-Silva AR, Brandão TB, Lopes MA, de Goes MF. Impact of head and neck radiotherapy on the mechanical behavior of composite resins and adhesive systems: a systematic review. Dent Mater. 2017 Nov;33(11):1229-43. doi: 10.1016/j.dental.2017.07.014.
McGuire JD, Mousa AA, Zhang BJ, Todoki LS, Huffman NT, Chandrababu KB et al. Extracts of irradiated mature human tooth crowns contain MMP-20 protein and activity. J Dent. 2014 May;42(5):626-35. doi: 10.1016/j.jdent.2014.02.013.
Gernhardt CR, KielbassaAM, Hahn P, Schaller HG. Tensile bond strengths of four different dentin adhesives on irradiated and non-irradiated human dentin in vitro. J Oral Rehabil. 2001 Sep;28(9):814-20.
The Brazilian Journal of Oral Sciences uses the Creative Commons license (CC), thus preserving the integrity of the articles in an open access environment.
Downloads
