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Patterns of dental anomalies in patients with nonsyndromic oral cleft


Cleft lip
Cleft palate
Dentition, mixed
Dentition, permanent
Tooth abnormalities

How to Cite

da Cas NV, Machado RA, Coletta RD, Carrinho Ayroza Rangel AL. Patterns of dental anomalies in patients with nonsyndromic oral cleft. Braz. J. Oral Sci. [Internet]. 2020 Aug. 27 [cited 2024 Apr. 18];19:e208729. Available from:


Aim: To characterize the patterns of dental anomalies (DA) in the mixed and permanent dentitions of patients with nonsyndromic oral cleft (NSOC). Methods: This cross-sectional, observational, case-control study included 173 patients, 61 with mixed dentition (NSOC=29 and control=32) and 112 with permanent dentition (NSOC=57 and control=55). All subjected were submitted to clinical and radiographic examination. Dental anomalies of eruption, number, size and shape outside the cleft area were considered. Results: Although there was no statistical significance among patients with mixed dentition, dental agenesis was the anomaly more common in this group. In patients with permanent dentition, a higher prevalence of DA in NSOC group compared to control group was observed (p=0.02). Gyroversion and dental agenesis were the DA more frequently observed in the permanent dentition and the second premolar was the tooth more affected (p=0.003). Mandible and the left side were more involved, and dental agenesis was more frequently found in patients with unilateral cleft lip with or without cleft palate (NSCL±P). Conclusion: Our findings show a higher frequency of DA in NSOCs than in the control group in patients with permanent dentition, mainly due to a higher occurrence of agenesis of second premolars in patients with unilateral NSCL±P.


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