Banner Portal
Prevalence and predisponent factors of molar-incisor hypomineralization in primary dentition
PDF

Keywords

Tooth demineralization
Dental enamel
Amelogenesis

How to Cite

1.
Lira A de LS de, Sousa FJ de, Sousa FDC de, Fontenele MKV, Ribeiro CKC, Ferreira LEG. Prevalence and predisponent factors of molar-incisor hypomineralization in primary dentition. Braz. J. Oral Sci. [Internet]. 2021 May 10 [cited 2024 Apr. 27];20(00):e211202. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8661202

Abstract

Aim: To evaluate the prevalence and predisposing factors for hypomineralization of second molars in children in primary dentition. Methods: A questionnaire was applied to parents to analyze predisposing factors and to assist in the diagnosis of hypomineralization in children between 2 and 6 years old, followed by an intraoral examination based on indices of non-fluorotic enamel defects in the primary dentition, according to the “Modified Index DDE” to determine demarcated opacity and HSPM presence / severity index to assess hypomineralization. Children from public and private schools were dived into two groups: if they presented HSPM-Group 1 (G1) and if they did not have HSPM-Control group (CG). Results: The most frequent predisposing factors associated with the child were Illness in the first year of life (X2= 6.49; p=0.01) and antibiotic use in the first year of life (X2= 41.82; p= 0.01). The factors associated with the mother were hypertension (X2= 9.36; p=0.01), infections during pregnancy (X2=14.80; p=0.01) and alcohol consumption during pregnancy (X2=97.33; p=0.01). There was a prevalence of 3.9% of HSPM in 14 children, with statistical difference regarding gender (X2 = 4.57; p <0.05), with boys presenting a higher frequency. In G1 hypomineralization was of the type with demarcated opacity, with more prevalent characteristics the yellowish spot, with moderate post-eruptive fracture and acceptable atypical restorations. All lesions were located in the labial region with 1/3 of extension. Conclusion: The prevalence of HSPM in children between 2 and 6 years old was 3.9%, with a predominance in males, with tooth 65 being the most affected. There was an association between HSPM and infection in the first year of life, as well as the use of antibiotics and sensitivity in the teeth affected by the lesion. There was an association between HSPM and hypertension, infection and mothers' alcohol use during pregnancy.

https://doi.org/10.20396/bjos.v20i00.8661202
PDF

References

Weerheijm KL, Duggal M, Mejare I, Papagiannoulis L, Koch G, Martens LC, et al. Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. Eur J Paediatr Dent. 2003;4(3)110-3.

Jalevik B. Prevalence and diagnosis of molar-incisor-ypomineralization (MIH): A systematic review. Eur Archs Paediatr Dent. 2010;11(2):59-64. doi: 10.1007/BF03262714.

Farias L, Laureano ICC, Alencar CRB, Cavalcanti AL. [Molar incisor hypomineralization: etiology, clinical characteristics and treatment]. Rev Cienc Med Biol. 2018;17(2):211-9. Portuguese. doi: 10.9771/cmbio.v17i2.27435.

Assunção CM, Girelli V, Sarti CS, Ferreira ES, Araujo FB, Rodrigues JA. [Molar incisor hypomineralization (MIH): case report and restorative treatment follow-up]. Rev Assoc Paul Cir Dent. 2014;68(4):346-50. Portuguese.

Weerheijm KL. Molar incisor hypomineralization (MIH). Eur J Paediatr Dent. 2003;4(3):115-20.

Fragelli CM, Jeremias F, Feltrin de Souza J, Paschoal MA, Cordeiro RCL, Santos-Pinto L. Longitudinal evaluation of the structural integrity of teeth affected by molar incisor hypomineralization. Caries Res. 2015;49(4):378-83. doi: 10.1159/000380858.

Negre-Barber A, Montiel-Company J, Boronat-Catalá M, Catalá-Pizarro M, Almerich JM. Hypomineralized second primary molars as predictor of molar incisor hypomineralization. Sci Rep. 2016;6(3):1-6. doi:10.1038/srep31929.

Elfrink MEC, Ghanim A, Manton DJ, Weerheijm KL. Standardised studies on molar incisor hypomineralization (MIH) and hypomineralized second primary molars (HSPM): a need. Eur Arch Paediatr Dent. 2015;16(3):247-55. doi: 10.1007/s40368-015-0179-7.

Mittal N, Sharma BB. Hypomineralised second primary molars: prevalence, defect characteristics and possible association with molar incisor hypomineralization in indian children. Eur Arch Paediatr Dent. 2015 Dec;16(6):441-7. doi: 10.1007/s40368-015-0190-z.

Luchesa CJ. Chaves Neto A. [Calculation of sample size in administration research]. Curitiba: Edição do autor; 2011. 27p. Portuguese.

Ghanim A, Elfrink M, Weerheijm K, Mariño R, Manton D. A practical method for use in epidemiological studies of enamel hpomineralization. Eur Arch Paediatr Dent. 2015;16(3):235-46. doi: 10.1007/s40368-015-0178-8.

Elfrink MEC, Ten Cate JM, Jaddoe VWV, Hofman A, Moll Ha, Veerkamp JSJ. Deciduous molar hypomineralization and molar incisor hypomineralization. J Dent Res. 2012 Jun;9(16):551- 5. doi: 10.1177/0022034512440450.

Owen M, Ghanim A, Elsby D, Manton, D. Hypomineralized second primary molars: prevalence, defect characteristics and relationship with dental caries in Melbourne preschool children. Aust Dent J. 2007;63(1):72-80. doi:10.1111/adj.12567.

Halalet F, Raslan N. Prevalence of hypomineralized second primary molars (HSPM) in Syrian preschool children. Eur Arch Paediatr Dent. 2020 Dec;21(6):711-7. doi: 10.1007/s40368-020-00520-2.

Sidhu N, Wang Y, Barrett E, Casas M. Prevalence and presentation patterns of enamel hypomineralization (MIH and HSPM) among paediatric hospital dental patients in Toronto, Canada: a cross-sectional study. Eur Arch Paediatr Dent. 2020;21(2):263-70. doi:10.1007/s40368-019-00477-x

Masumo R, Bardsen A, Astrom AN. Developmental defects of enamel in primary teeth and association with early life course events: a study of 6-36 month old children in Manyara, Tanzania. BMC Oral Health. 2013 May;13(21):1-11. doi: 10.1186/1472-6831-13-21.

Aine L, Backström MC, Mäki R, Kuusela AL, Koivisto AM, Ikonen RS, et al. Enamel defects in primary and permanent teeth in children born prematurely. J Oral Pathol Oral Med. 2000;29(8):403-9. doi:10.1034/j.1600-0714.2000.290806.x.

Sé MJSF, Ribeiro APD, Dos Santos-Pinto LAM, Loiola RC, Cordeiro R, Cabral RN, et al. Are hypomineralized primary molars and canines associated with molar-incisor hHypomineralization? Pediatr Dent. 2017 Nov;39(7):445-9.

Serna-Muñoz C, Ortiz-Ruiz AJ, Silva AP, Bravo-González LA, Vicente A. Second primary molar hypomineralization and drugs used during pregnancy and infancy. A systematic review. Clin Oral Invest. 2020 Mar;24(3):287-97. doi:10.1007/s00784-019-03007-7.

Kemoli AM. Prevalence of molar incisor hypomineralization in six to eight year-olds in two rural divisions in Kenya. East Afr Med J. 2008;85(10):514-9.

Jeremias F, de Souza JF, Silva CM, Cordeiro RC, Zuanon AC, Santos-Pinto L. Dental caries experience and molar-incisor hypomineralization. Acta Odontol Scand. 2013 Jan;71(3-4):870-6. doi: 10.3109/00016357.2012.734412.

Subramaniam P, Gupta T, Sharma A. Prevalence of molar incisor hypomineralization in 7–9-year-old children of Bengaluru City, India. Contemp Clin Dent. 2016 Jan/Mar;7(1):11-5. doi: 10.4103/0976-237X.177091.

Alaluusua S, Lukinmaa L, Vartiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated dibenzo-p-dioxins and dibenzofurans via mother's milk may cause developmental defects in the child’s teeth. Environ Toxicol Pharmacol. 1996 May;1(3):193-7. doi:10.1016/1382-6689(96)00007-5.

Garot E, Rouas P, d’Incau E, Lenoir N, Manton D, Couture C. Mineral dentisty of hypomineralized and sound enamel. Bull Group Int Sci Stomatol Odontol. 2016;53(1):33-6

Oyedele TA, Folayan MO, Oziegbe EO. Hypomineralized second primary molars: prevalence, pattern and associated co-morbidities in 8- to 10-year-old children in Ile-Ife, Nigeria. BMC Oral Health. 2016;16(1):65. doi:10.1186/s12903-016-0225-9.

Buchgraber B, Kqiku L, Ebeleseder KA. Molar incisor hypomineralization: proportion and severity in primary public school children in Graz, Austria. Clin. Oral Investig. Berlin. 2017 Mar;22(2):757-62. doi: 10.1007/s00784-017-2150-y.

Wuollet E, Laisi S, Salmela E, Ess A, Alaluusua S. Molar-incisor hypomineralization and the association with childhood illnesses and antibiotics in a group of Finnish children. Acta Odontol Scand. 2016 May;74(5):1-7. doi: 10.3109/00016357.2016.1172342.

Faustino-Silva DD, Rocha AF, da Rocha BS, Stein C. Use of antibiotics in early childhood and dental enamel defects in 6- to 12-year-old children in primary health care. Acta Odontol Latinoam. 2020;33(1):6-13.

Lopes-Fatturi A, Menezes JVNB, Fraiz FC, Assunção LRDS, de Souza JF. Systemic exposures associated with hypomineralized primary second molars. Pediatr Dent. 2019;41(5):364-70.

Bullio Fragelli CM, Jeremias F, Feltrin de Souza J, Paschoal MA, de Cássia Loiola Cordeiro R, Santos-Pinto L. Longitudinal evaluation of the structural integrity of teeth affected by molar incisor hypomineralization. Caries Res. 2015;49(4):378-83. doi: 10.1159/000380858.

Temilola OD, Folayan MO, Oyedele T. The prevalence and pattern of deciduous molar hypomineralization and molar-incisor hypomineralization in children from a suburban population in Nigeria. BMC Oral Health. 2015 Jun;15(1):73-9. doi: 10.1186/s12903-015-0059-x.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2021 Brazilian Journal of Oral Sciences

Downloads

Download data is not yet available.