A simplified protocol to determine total fluoride concentration in NaF/ silica-based toothpastes

Authors

DOI:

https://doi.org/10.20396/bjos.v19i0.8661689

Keywords:

Fluorides, Toothpastes, Silicic acid, Dentifrices, Ion-selective electrodes

Abstract

Aim: To determine total fluoride (TF) concentration in Na2FPO3/Ca-based toothpastes, using fluoride ion selective electrode (F-ISE) by the direct technique, it is necessary to use acid (Ac+) to hydrolyze the FPO3 2- ion and to dissolve insoluble fluoride salts bound to the abrasive. For NaF/silicabased toothpastes, the use of acid is not necessary (Ac-) and a simplified protocol could be followed. Methods: Thus, we evaluated TF concentration in seven brands of NaF/silicabased toothpastes, following the validated conventional Cury’s protocol (Ac+) or a simplification of this protocol (Ac-). Fluoride was analyzed with ISE calibrated with fluoride standard solutions prepared in the same conditions as the samples (Ac+ or Ac-). Results: The mean (±SD; n=21) of TF concentrations (μg F/g) found by Ac+ (971.3±191.2) and Ac- (982.4±201.3) protocols were not statistically different (t test, p=0.22). The TF concentrations found agree with those declared by the manufacturers, except for one toothpaste imported from China. Conclusion: The findings suggest that the determination of fluoride in NaF/silica-based toothpastes can be accurately made using a simplified protocol of analysis.

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Author Biographies

Jenniffer Quiroz-Torres, Universidad Peruana Cayetano Heredia

Assistant Professor, Academic Department of Dentistry for Children and Adolescents, Faculty of Stomatology, Universidad Peruana Cayetano Heredia, Lima, Peru.

Cinthia Pereira Machado Tabchoury, University of Campinas

Associate Professor of Biochemistry, Department of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.

Carlos Liñán-Durán, Universidad Peruana Cayetano Heredia

Assistant Professor, Academic Department of Dentistry for Children and Adolescents, Faculty of Stomatology, Universidad Peruana Cayetano Heredia, Lima, Peru.

Antonio Pedro Ricomini-Filho, University of Campinas

Assistant Professor of Biochemistry, Department of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.

Ailin Cabrera-Matta, Universidad Peruana Cayetano Heredia

Associate Professor, Academic Department of Dentistry for Children and Adolescents, Faculty of Stomatology, Universidad Peruana Cayetano Heredia, Lima, Peru.

Jaime Aparecido Cury, University of Campinas

Department of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.

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Published

2020-12-11

How to Cite

1.
Quiroz-Torres J, Tabchoury CPM, Liñán-Durán C, Ricomini-Filho AP, Cabrera-Matta A, Cury JA. A simplified protocol to determine total fluoride concentration in NaF/ silica-based toothpastes. Braz. J. Oral Sci. [Internet]. 2020 Dec. 11 [cited 2022 Oct. 7];19:e201689. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8661689

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