Antimicrobial potential of essential oils mouthrinses with and without alcohol

a randomized clinical trial

Authors

  • Matheus Grunevald Federal University of Rio Grande do Sul
  • Rômulo Cantarelli Federal University of Rio Grande do Sul
  • Harry Juan Rivera Oballe Federal University of Rio Grande do Sul
  • Thais de Cássia Negrini São Paulo State University
  • Rodrigo Alex Arthur Federal University of Rio Grande do Sul https://orcid.org/0000-0001-8107-413X
  • Eduardo Liberato da Silva Federal University of Rio Grande do Sul
  • Tiago Luis Herpich Federal University of Rio Grande do Sul
  • Francisco Wilker Mustafa Gomes Muniz Federal University Rio Grande do Sul https://orcid.org/0000-0002-3945-1752

DOI:

https://doi.org/10.20396/bjos.v20i00.8663867

Keywords:

Alcohols, Oils volatile, Bacteria, Mouthwashes, Taste perception

Abstract

Aim: This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p<0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p<0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). Conclusion: Mouthrinse containing EO without alcohol presented a better taste perception when compared to the EO with alcohol, but no difference was observed in the antimicrobial potential of both EO solutions after a single rinse protocol.

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Author Biographies

Matheus Grunevald, Federal University of Rio Grande do Sul

Student fellow, Federal University Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Rômulo Cantarelli, Federal University of Rio Grande do Sul

Student fellow, Post-Graduate Program in Dentistry, Federal University Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Harry Juan Rivera Oballe , Federal University of Rio Grande do Sul

Student fellow, Post-Graduate Program in Dentistry, Federal University Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Thais de Cássia Negrini, São Paulo State University

Post-Doctoral Student fellow, Post-Graduate Program in Bioscience and Biotechnology applied to Pharmacy, Department of Clinical Analysis, São Paulo State University, Araraquara, Brazil.

Rodrigo Alex Arthur, Federal University of Rio Grande do Sul

Professor of Oral Microbiology and Biochemistry and Cariology, Department of Preventive and Community Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul Brazil.

Eduardo Liberato da Silva , Federal University of Rio Grande do Sul

Master degree student, Post-Graduate Program in Dentistry, Federal University Rio Grande do Sul, Porto Alegre, Rio Grande do Sul Brazil.

Tiago Luis Herpich, Federal University of Rio Grande do Sul

Student fellow, Federal University Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Francisco Wilker Mustafa Gomes Muniz, Federal University Rio Grande do Sul

Professor of Periodontology, Department of Semiology and Clinic, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.

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Published

2021-04-16

How to Cite

1.
Grunevald M, Cantarelli R, Oballe HJR, Negrini T de C, Arthur RA, Silva EL da, Herpich TL, Muniz FWMG. Antimicrobial potential of essential oils mouthrinses with and without alcohol: a randomized clinical trial. Braz. J. Oral Sci. [Internet]. 2021Apr.16 [cited 2021Dec.4];20(00):e213867. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8663867

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Original Research

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