Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria

Authors

DOI:

https://doi.org/10.20396/bjos.v21i00.8666341

Keywords:

Dental caries, Glass ionomer cement, Fluorides, topical

Abstract

Treatment of dental caries in children still remains challenging due to lack of cooperation with conventional treatment modalities. Recently, the use of Silver Diamine Fluoride (SDF) has proved useful in addressing this challenge. Aim: This clinical trial aimed to evaluate the effectiveness of Silver Diamine Fluoride (SDF) in arresting caries in children in Lagos, Nigeria. Methods: This was a phase III balanced randomized controlled school based interventional study on 240 children. The study group was treated with SDF while GIC was used in the control group. Follow up visits in 2 weeks, 1 month, and 3 months were carried out to assess the treatment outcome. Inferential statistics with the use of Pearson Chi-square test and Independent Student t-test were used at 5% level of significance. Results: There was significant relationship between SDF and caries arrest in 2 weeks, 1 month and 3 months’ assessment period (p = 0.001). The control group showed continuous decline (71.7%, 54.3% and 50.9%) in restorative success from 2 weeks to 3 months respectively. The mean ± SD and Confidence Interval (CI) of arrested caries in the SDF group were 113± 1.24 and 113.1 – 113.5 respectively. In the control group the mean ± SD and CI of restorative success were 69.3±11.8 and 67.2 – 71.4. The effect size was 5.24. Conclusion: The result of the study showed that SDF was effective in arresting caries in children without any harm and there was statistically significant difference in the use of 38% SDF in arresting caries in children.

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Author Biographies

Moses Okechukwu Azouru, Lagos State University Teaching Hospital

Department of Child Dental Health, Lagos State University Teaching Hospital, Lagos, Nigeria.

Modupe Olufunmilayo Ashiwaju, University of Lagos

Department of Child Dental Health, College of Medicine, University of Lagos, Lagos, Nigeria.

Augustine Edomwonyi, University of Medical Sciences

Department of Preventive Dentistry, Faculty of Dentistry, University of Medical Sciences, Ondo State, Nigeria.

Afolabi Oyapero, Lagos State University College of Medicine

Department of Preventive Dentistry, Faculty of Dentistry, Lagos State University College of Medicine, Lagos, Nigeria.

Bola Obisesan, National Postgraduate Medical College of Nigeria

Faculty of Family Dentistry, National Postgraduate Medical College of Nigeria, Lagos, Nigeria.

Aderinsola Omotuyole, Lagos State University College of Medicine

Department of Child Dental Health, Faculty of Dentistry, Lagos State University College of Medicine, Lagos, Nigeria.

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Published

2021-11-03

How to Cite

1.
Azouru MO, Ashiwaju MO, Edomwonyi A, Oyapero A, Obisesan B, Omotuyole A. Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria . Braz. J. Oral Sci. [Internet]. 2021 Nov. 3 [cited 2022 May 25];21(00):e226341. Available from: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8666341

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Original Research