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A survey on brazilian dentists’ awareness, perception, and knowledge of bisphosphonates


Drug utilization

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Nunes RLO, Anjos NR dos, Lima LHF, Viana APC, Pereira L de Ávila, Bruzinga FFB, et al. A survey on brazilian dentists’ awareness, perception, and knowledge of bisphosphonates. Braz. J. Oral Sci. [Internet]. 2023 Mar. 24 [cited 2024 Jun. 15];22(00):e237544. Available from:


Aim: The purpose of the study was to analyze the knowledge of dentists in Belo Horizonte, Brazil, about bisphosphonates and their clinical implications. Methods: A cross-sectional questionnaire-based study was conducted with a convenience sample of dentists in Belo Horizonte, in a period of 8 weeks. The questionnaire was self-applied and was structured with 10 items about the dentists’ demographic characteristics, professional profile, and knowledge about bisphosphonates. Associations in the data were analyzed by with the Fischer’s exact test with a significance level of 5%. Results: Of the 214 participating dentists, 163 (76.17%) were women, and 51 (23.83%) were men, with age ranged for 21 to 73 years (mean of 30 years) and mean of 6 years of professional activity. Nearly half (106/49.53%) reported having knowledge about bisphosphonates, and undergraduate courses were the primary source of such information (73/34.11%). Osteoporosis was the most identified indication for use (75/35.04%), although no participants correctly identified all indications. Regarding the drugs’ side effects, only three dentists (1.40%) could correctly identify all responses, with bone necrosis being recognized by the majority (88/41.12%). Sodium alendronate (54/25.23%) and sodium ibandronate (15/7.01%) were the most identified examples of bisphosphonates. Last, only nine dentists (4.20%) could identify all examples of the drugs, and their capacity was associated with self-reported knowledge (p<0.05). Conclusions: More information about bisphosphonates should be disseminated in Belo Horizonte, ideally via better approaches in local undergraduate and postgraduate courses. Until then, knowledge of the basic aspects of bisphosphonates will remain limited.


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Copyright (c) 2022 Raquel Laís Ottoni Nunes, Nicole Ribeiro dos Anjos, Luciano Henrique Ferreira Lima, Ana Paula Cota Viana, Larissa de Ávila Pereira, Fábio Fernandes Borém Bruzinga, Soraya de Mattos Camargo Grossmann


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