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Assessing the bleaching effect of an experimental stabilized chlorine dioxide agent used for internal bleaching purposes


Tooth bleaching
Chlorine compounds
Dental materials

How to Cite

Hirata BS, Berger SB, Guiraldo RD, Felizardo KR, Ramos NBP, Lopes MB. Assessing the bleaching effect of an experimental stabilized chlorine dioxide agent used for internal bleaching purposes. Braz. J. Oral Sci. [Internet]. 2022 Jul. 4 [cited 2024 May 19];21(00):e227878. Available from:


Aim: Assessing the intracoronal bleaching effectiveness of an experimental chlorine dioxide product, based on the walking bleach technique. Methods: Extracted bovine incisors were artificially stained with bovine blood and filled with zinc phosphate cement at cementoenamel junction level. Teeth were divided into 3 groups (n=10): (SP) sodium perborate added with distilled water, (CD) chlorine dioxide and (C) control – dry cotton inserted into the pulp chamber. Bleaching agents were used at 0, 7 and 14 days. VITA Easyshadetm (ΔEab) was used to analyze tooth color at the 7th, 14th and 21st days, based on the CIE2000 system. Data were analyzed through ANOVA and Tukey’s test. Results: There were no statistically significant differences in Δb, ΔE, ΔE00 and ΔWID between CD and the control group. These parameters have shown significant differences between CD and SP, which differed from the control. However, they did not show significant differences either in the control group or in CD at the 7th, 14th and 21st days. Values recorded for SP at the 7th day differed from those recorded at the 14th and 21st days. Δa has shown differences within the same group at the 7th, 14th and 21st days. There was no difference between groups, when they were compared at the same day (7th and 14th). The control group differed from SP at the 21st day. CD did not differ from the other two groups. ΔL did not show differences between groups and times. Conclusion: Stabilized chlorine dioxide (0.07%, at pH 3.5) should not be used as intracoronal bleaching agent along with the walking bleach technique.


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Copyright (c) 2021 Bruno Shindi Hirata, Sandrine Bittencourt Berger, Ricardo Danil Guiraldo, Klissia Romero Felizardo, Nádia Buzignani Pires Ramos, Murilo Baena Lopes


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