Abstract
Objective: The aim of this study was to assess the impact of xerostomia, the subjective perception of dry mouth, on the oral health-related quality of life of older adults. Methods: This study involved 131 individuals who participated in the AcampaVida extension project between 2015 and 2018 in the city of Santa Maria, Rio Grande do Sul, Brazil. A structured questionnaire obtained demographic, socioeconomic, behavioral, and self-reported information about xerostomia. Also, the Brazilian version of the Oral Health Impact Profile-14 (OHIP-14) was used to assess oral health-related quality of life. Data were analyzed in STATA 14.0, and the association of xerostomia with predictive quality of life variables was performed using unadjusted and adjusted Poisson regression. Results: OHIP-14 scores were 28% higher in individuals with xerostomia. Regarding the questionnaire domains, the highest scores comprised physical pain and psychological discomfort in individuals with xerostomia. Conclusion: The results indicate that xerostomia had a negative impact on the oral health-related quality of life of the assessed older adults.
References
1. Villa A, Wolff A, Narayana N, Dawes C, Aframian DJ, Lynge Pedersen AM, et al. World Workshop on Oral Medicine VI: a systematic review of medication-induced salivary gland dysfunction. Oral Dis. 2016 Jul;22(5):365-82. doi: 10.1111/odi.12402.
2. Agostini BA, Cericato GO, Silveira ERD, Nascimento GG, Costa FDS, Thomson WM, et al. How Common is Dry Mouth? Systematic review and meta-regression analysis of prevalence estimates. Braz Dent J. 2018 Nov-Dec;29(6):606-18. doi: 10.1590/0103-6440201802302.
3. Tanasiewicz M, Hildebrandt T, Obersztyn I. Xerostomia of various etiologies: a review of the literature. Adv Clin Exp Med. 2016 Jan-Feb;25(1):199-206. doi: 10.17219/acem/29375.
4. Kapourani A, Kontogiannopoulos KN, Manioudaki AE, Poulopoulos AK, Tsalikis L, Assimopoulou AN, et al. A review on xerostomia and its various management strategies: the role of advanced polymeric materials in the treatment approaches. Polymers (Basel). 2022 Feb;14(5):850. doi: 10.3390/polym14050850.
5. Choi JH, Kim MJ, Kho HS. Oral health-related quality of life and associated factors in patients with xerostomia. Int J Dent Hyg. 2021 Aug;19(3):313-22. doi: 10.1111/idh.12528.
6. Millsop JW, Wang EA, Fazel N. Etiology, evaluation, and management of xerostomia. Clin Dermatol. 2017 Sep-Oct;35(5):468-76. doi: 10.1016/j.clindermatol.2017.06.010.
7. Graziani F, Tsakos G. Patient-based outcomes and quality of life. Periodontol 2000. 2020 Jun;83(1):277-94. doi: 10.1111/prd.12305.
8. Spanemberg JC, Cardoso JA, Slob EMGB, López-López J. Quality of life related to oral health and its impact in adults. J Stomatol Oral Maxillofac Surg. 2019 Jun;120(3):234-239. doi: 10.1016/j.jormas.2019.02.004.
9. Barbosa TS, Mialhe FL, Castilho ARF, Gavião MBD. [Quality of life and oral health in children and adolescents: conceptual and methodological aspects]. Physis. 2010;20(1):283-300. Portuguese. doi: 10.1590/S0103-73312010000100015.
10. Chimbinha ÍGM, Ferreira BNC, Miranda GP, Guedes RS. Oral-health-related quality of life in adolescents: umbrella review. BMC Public Health. 2023 Aug;23(1):1603. doi: 10.1186/s12889-023-16241-2.
11. Menezes KE, Pereira CAS, Pedro ACB, Dias AG. [Assessment of the impact of dental caries on the quality of life of children aged 6 to 12 years old treated at the dental clinic of Faculdade São Lucas]. Rev Odontol Univ Cid Sao Paulo 2009;21(1):24–30. Portuguese.
12. Glick M, Williams DM, Kleinman DV, Vujicic M, Watt RG, Weyant RJ. A new definition for oral health developed by the FDI World Dental Federation opens the door to a universal definition of oral health. J Am Dent Assoc. 2016 Dec;147(12):915-7. doi: 10.1016/j.adaj.2016.10.001.
13. Sischo L, Broder HL. Oral health-related quality of life: what, why, how, and future implications. J Dent Res. 2011 Nov;90(11):1264-70. doi: 10.1177/0022034511399918.
14. Niklander S, Veas L, Barrera C, Fuentes F, Chiappini G, Marshall M. Risk factors, hyposalivation and impact of xerostomia on oral health-related quality of life. Braz Oral Res. 2017 Jan;31:e14. doi: 10.1590/1807-3107BOR-2017.vol31.0014.
15. IBGE. Brazilian Institute of Geography and Statistics. [Cities and states. Santa Maria] 2022 [cited 2023 Dec 2]. Available from: https://www.ibge.gov.br/cidades-e-estados/rs/santa-maria.html. Portuguese.
16. Han P, Suarez-Durall P, Mulligan R. Dry mouth: a critical topic for older adult patients. J Prosthodont Res. 2015 Jan;59(1):6-19. doi: 10.1016/j.jpor.2014.11.001. Epub 2014 Dec 9.
17. Lu TY, Chen JH, Du JK, Lin YC, Ho PS, Lee CH, et al. Dysphagia and masticatory performance as a mediator of the xerostomia to quality of life relation in the older population. BMC Geriatr. 2020 Dec;20(1):521. doi: 10.1186/s12877-020-01901-4.
18. Ikebe K, Matsuda K, Morii K, Wada M, Hazeyama T, Nokubi T, et al. Impact of dry mouth and hyposalivation on oral health-related quality of life of elderly Japanese. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb;103(2):216-22. doi: 10.1016/j.tripleo.2005.12.001. Epub 2006 Mar 20.
19. MacLeod S, Musich S, Hawkins K, Alsgaard K, Wicker ER. The impact of resilience among older adults. Geriatr Nurs. 2016 Jul-Aug;37(4):266-72. doi: 10.1016/j.gerinurse.2016.02.014.
20. Johnell K, Fastbom J. Comparison of prescription drug use between community-dwelling and institutionalized elderly in Sweden. Drugs Aging. 2012 Sep;29(9):751-8. doi: 10.1007/s40266-012-0002-7.
21. Slade GD, Strauss RP, Atchison KA, Kressin NR, Locker D, Reisine ST. Conference summary: assessing oral health outcomes--measuring health status and quality of life. Community Dent Health. 1998 Mar;15(1):3-7.
22. Abanto J, Carvalho TS, Mendes FM, Wanderley MT, Bönecker M, Raggio DP. Impact of oral diseases and disorders on oral health-related quality of life of preschool children. Community Dent Oral Epidemiol. 2011 Apr;39(2):105-14. doi: 10.1111/j.1600-0528.2010.00580.x. Epub 2010 Oct 5.

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Copyright (c) 2026 Mariana Marquezan, Brenda Hammes do Nascimento , Maria Eduarda Maldonado Silva, Jessica Klöckner Knorst, Luísa Helena do Nascimento Tôrres, Leandro José Corrêa Harb
