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Síndrome Metabólica (SM) é o conjunto de fatores de risco associados ao desenvolvimento de doenças cardiovasculares e diabetes tipo 2. O acúmulo de tecido adiposo na região abdominal é associado à resistência à insulina, condições consideradas essenciais para o desencadeamento das alterações que constituem a SM. O objetivo deste trabalho foi abordar questões relevantes em relação aos aspectos clínicos da SM e descrever fatores modificáveis (hábitos alimentares e atividade física) associados ao seu desenvolvimento em adolescentes. Especialmente entre àqueles com excesso de peso, as alterações metabólicas, quando ainda não detectadas, tendem a se manifestarem com o avanço da idade, o que ressalta a discussão em relação à prevenção e/ou tratamento da obesidade/SM, dislipidemias e demais morbidades associadas. Em adolescentes, a adoção de hábitos alimentares saudáveis e a prática regular de atividades físicas/exercícios mostram-se relevantes para a prevenção e/ou tratamento da SM e das alterações metabólicas isoladamente.
Referências
Steinberger J, Daniels SR, Eckel RH, Hayman L, Lustig RH, Mccrindle B, et al. Progress and challenges in metabolic syndrome in children and adolescents. Circulation. 2009;119(4):628-47.
Alberti KGMM, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome. Circulation. 2009;120(16):1640-45.
Reaven GM. Banting lecture 1988. Role of insulin resistence in human disease. Diabetes. 1988;37(12):1595- 1607.
Raj M. Obesity and cardiovascular risk in children and adolescents. Indian J Endocrinol Metab. 2012;16(1):13-9.
Després J, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, et al. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol. 2008;28(6):1039-49.
Lee S, Bacha F, Gungor N, Arslanian S. Comparison of different definitions of pediatric metabolic syndrome: relation to abdominal adiposity, insulin resistance, adiponectin, and inflammatory biomarkers. J Pediatr. 2008;152(2):177-84.
Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365(9468):1415-28.
Caballero AE. Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease. Obes Res. 2003;11(11):1278-89.
International Diabetes Federation. The IDF consensus definition of the metabolic syndrome in children and adolescents. 2007 [cited 2012 Oct 18]. Available from: http://www.idf.org/metabolic-syndrome/children
Dietz WH. Overweight in childhood and adolescence. N Engl J Med. 2004;350(9):855-57.
Dhuper S, Sakowitz S, Daniels J, Buddhe S, Cohen HW. Association of lipid abnormalities with measures and severity of adiposity and insulin resistance among overweight children and adolescents. J Clin Hypertens. 2009;11(10):594-600.
Bankoski A, Harris TB, McClain JJ, Brychta RJ, Caserotti P, Chen KY, et al. Sedentary activity associated with Metabolic Syndrome independent of physical activity. Diabetes Care. 2011;34(2):497-503.
Singh B, Arora S, Goswami B, Mallika V. Metabolic syndrome: A review of emerging markers and management. Diab Met Syndr: Clin Res Rev. 2009;3(4):497-503.
Pan Y, Pratt CA. Metabolic syndrome and its association with diet and physical activity in US adolescents. J Am Diet Assoc. 2008;108(2):276-86.
Instituto Brasileiro de Geografia e Estatística. Pesquisa de Orçamentos Familiares – POF 2008-2009. Antropometria e estado nutricional de crianças, adolescentes e adultos no Brasil. Rio de Janeiro: IBGE; 2010.
Instituto Brasileiro de Geografia e Estatística. Pesquisa de Orçamentos Familiares – POF 2008-2009. Análise do consumo alimentar pessoal no Brasil. Rio de Janeiro: IBGE; 2011.
Conselho Nacional de Segurança Alimentar e Nutricional. Plano intersetorial de prevenção e controle da obesidade [acesso em 23 out 2012]. Disponível em: http://www4.planalto.gov.br/consea/noticias/documentos/ plano-intersetorial-de-prevencao-e-controle-daobesidade/ view?searchterm=obesidade
Weiss R. Fat distribution and storage: how much, where, and how? Eur J Endocrinol. 2007;157(Suppl. 1):39-45.
May AL, Kuklina EV, Yoon PW. Prevalence of Cardiovascular Disease Risk Factors Among US Adolescents, 1999-2008. Pediatrics. 2012;129(6):1035-41.
Park J, Hilmers DC, Mendoza JA, Stuff JE, Liu Y, Nicklas TA. Prevalence of metabolic syndrome and obesity in adolescents aged 12 to 19 years: comparison between the United States and Korea. J Korean Med Sci. 2010;25(1):75- 82.
Sellers EA, Singh GR, Sayers SM. Large waist but low body mass index: The Metabolic Syndrome in Australian aboriginal children. J Pediatr. 2008;153(2):222-227.
Spolidoro JV, Pitrez Filho ML, Vargas LT, Santana JC, Pitrez E, Hauschild JA, et al. Waist circumference in children and adolescents correlate with metabolic syndrome and fat deposits in young adults. Clin Nutr. 2012. DOI: 10.1016/j.clnu.2012.05.020
Camhi SM, Kuo J, Young DR. Identifying adolescent metabolic syndrome using Body Mass Index and waist circumference. Prev Chronic Dis. 2009;5(4):1-9.
Brambilla P, Bedogni G, Moreno LA, Goran MI, Gutin B, Fox KR, et al. Crossvalidation of anthropometry against magnetic resonance imaging for the assessment of visceral and subcutaneous adipose tissue in children. Int J Obes. 2006;30(1):23-30.
Faria ER, Franceschini SCC, Peluzio MCG, Sant’ana LFR, Priore SE. Correlação entre variáveis de composição corporal e metabólica em adolescentes do sexo feminino. Arq Bras Cardiol. 2009;93(2):119-27.
Hirschler V, Ruiz A, Romero T, Dalamon R, Molinari C. Comparison of different anthropometric indices for identifying insulin resistance in schoolchildren. Diabetes Technol Ther. 2009;11(9):615-21.
Gómez-Ambrosi J, Silva C, Galofré JC, Escalada J, Santos S, Gil MJ, et al. Body adiposity and Type 2 Diabetes: increased risk with a high body fat percentage even having a normal BMI. Obesity. 2011;19(7):1439-44.
Bamba V, Rader DJ. Obesity and atherogenic dyslipidemia. Gastroenterology. 2007;132(6):2181-90.
Hannon TS, Bacha F, Lee SJ, Janosky J, Arslanian SA. Use of markers of dyslipidemia to identify overweight youth with insulin resistance. Pediatr Diabetes. 2006;7(5):260-66.
Brunzell JD. Hypertriglyceridemia. N Engl J Med. 2007;357(10):1009-17.
Grundy SM. Hypertriglyceridemia, insulin resistance, and the Metabolic Syndrome. Am J Cardiol. 1999;83(9):25-29.
Savel J, Lafitte M, Pucheu Y, Pradeau V, Tabarin A, Couffinhal T. Very low levels of HDL cholesterol and atherosclerosis, a variable relationship – a review of LCAT deficiency. Vasc Health Risk Manag. 2012;8:357-61.
Tabet F, Rye K. High-density lipoproteins, inflammation and oxidative stress. Clin Sci. 2009;116(2):87-98.
Bitzur R, Cohen H, Kamari Y, Shaish A, Harats D. Triglycerides and HDL cholesterol. Stars or second leads in diabetes? Diabetes Care. 2009;32(Suppl. 2):373-77.
Soran H, Hama S, Yadav R, Durrington PN. HDL functionality. Curr Opin Lipidol. 2012;23(4):353-66.
Barter P. HDL-C: role as a risk modifier. Atheroscler Suppl. 2011;12(3):267-70.
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